PrimePCR™ ddPCR™ Expression Probe Assay: HIF1A, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050075; exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033624
Chromosome Location:   14:62207736-62207876question
Amplicon Length:   111

Gene Information

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1) which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes including those involved in energy metabolism angiogenesis apoptosis and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq Jul 2011]

Gene Symbol:   HIF1A
Gene Name:   hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Aliases:   HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000100644
Entrez:   3091
UniGene:   Hs.597216
Chromosome Mapping:   14q23.2

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