PrimePCR™ ddPCR™ Expression Probe Assay: EP300, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050044; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033568
Chromosome Location:   22:41513200-41513329question
Amplicon Length:   100

Gene Information

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha) and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq Jul 2008]

Gene Symbol:   EP300
Gene Name:   E1A binding protein p300
Aliases:   KAT3B, RSTS2, p300
RefSeq:   NC_000022.10 NG_009817.1 NT_011520.12
Ensembl:   ENSG00000100393
Entrez:   2033
UniGene:   Hs.517517
Chromosome Mapping:   22q13.2

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