PrimePCR™ ddPCR™ Expression Probe Assay: CYB5R3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050020; exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033524
Chromosome Location:   22:43024186-43024282question
Amplicon Length:   67

Gene Information

This gene encodes cytochrome b5 reductase which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids in cholesterol biosynthesis and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq Jan 2010]

Gene Symbol:   CYB5R3
Gene Name:   cytochrome b5 reductase 3
Aliases:   B5R, DIA1
RefSeq:   NC_000022.10 NG_012194.1 NT_011520.12
Ensembl:   ENSG00000100243
Entrez:   1727
UniGene:   Hs.561064
Chromosome Mapping:   22q13.31-qter,22q13.2-q13.31

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