This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050000; exonic
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases also known as extracellular signal-regulated kinases (ERKs) act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation this kinase translocates to the nucleus of the stimulated cells where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein but differing in the UTRs have been reported for this gene. [provided by RefSeq Jul 2008]