PrimePCR™ ddPCR™ Expression Probe Assay: DAZL, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049920; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033335
Chromosome Location:   3:16638259-16638379question
Amplicon Length:   91

Gene Information

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jun 2010]

Gene Symbol:   DAZL
Gene Name:   deleted in azoospermia-like
Aliases:   DAZH, DAZL1, DAZLA, MGC26406, SPGYLA
RefSeq:   NC_000003.11 NT_022517.18 NG_023329.1
Ensembl:   ENSG00000092345
Entrez:   1618
UniGene:   Hs.131179
Chromosome Mapping:   3p24.3

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