PrimePCR™ ddPCR™ Expression Probe Assay: IL5RA, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049893; exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033280
Chromosome Location:   3:3144400-3146593question
Amplicon Length:   82

Gene Information

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3) colony stimulating factor 2 (CSF2/GM-CSF) and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin) which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq Jul 2011]

Gene Symbol:   IL5RA
Gene Name:   interleukin 5 receptor, alpha
Aliases:   CD125, CDw125, HSIL5R3, IL5R, MGC26560
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000091181
Entrez:   3568
UniGene:   Hs.68876
Chromosome Mapping:   3p26-p24

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