PrimePCR™ ddPCR™ Expression Probe Assay: PTHLH, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049830; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033172
Chromosome Location:   12:28116578-28116669question
Amplicon Length:   62

Gene Information

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone PTHR1 is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites in-frame and downstream of the initiator AUG codon to give rise to nuclear forms of this hormone. [provided by RefSeq Jul 2008]

Gene Symbol:   PTHLH
Gene Name:   parathyroid hormone-like hormone
Aliases:   BDE2, HHM, MGC14611, PLP, PTHR, PTHRP
RefSeq:   NC_000012.11 NT_009714.17 NG_023197.1
Ensembl:   ENSG00000087494
Entrez:   5744
UniGene:   Hs.591159
Chromosome Mapping:   12p12.1-p11.2

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