PrimePCR™ ddPCR™ Expression Probe Assay: CHRNA3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049718; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033055
Chromosome Location:   15:78911120-78911215question
Amplicon Length:   66

Gene Information

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq Nov 2009]

Gene Symbol:   CHRNA3
Gene Name:   cholinergic receptor, nicotinic, alpha 3
Aliases:   LNCR2, MGC104879, NACHRA3, PAOD2
RefSeq:   NC_000015.9 NG_023328.1 NT_010194.17 NG_016143.1
Ensembl:   ENSG00000080644
Entrez:   1136
UniGene:   Hs.89605
Chromosome Mapping:   15q24

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