PrimePCR™ ddPCR™ Expression Probe Assay: CEACAM1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049700; exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033040
Chromosome Location:   19:43016508-43016597question
Amplicon Length:   60

Gene Information

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family the CEA cell adhesion molecules and the pregnancy-specific glycoproteins are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently it was found to be a cell-cell adhesion molecule detected on leukocytes epithelia and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein including roles in the differentiation and arrangement of tissue three-dimensional structure angiogenesis apoptosis tumor suppression metastasis and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported but the full-length nature of all variants has not been defined. [provided by RefSeq May 2010]

Gene Symbol:   CEACAM1
Gene Name:   carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Aliases:   BGP, BGP1, BGPI
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000079385
Entrez:   634
UniGene:   Hs.512682
Chromosome Mapping:   19q13.2

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