PrimePCR™ ddPCR™ Expression Probe Assay: ACTL6B, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049653; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032969
Chromosome Location:   7:100240732-100240862question
Amplicon Length:   101

Gene Information

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold which is an ATP-binding cleft as a common feature. The ARPs are involved in diverse cellular processes including vesicular transport spindle orientation nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin specifically in the brain. [provided by RefSeq Jul 2008]

Gene Symbol:   ACTL6B
Gene Name:   actin-like 6B
Aliases:   ACTL6, BAF53B
RefSeq:   NC_000007.13 NG_007989.1 NT_007933.15
Ensembl:   ENSG00000077080
Entrez:   51412
UniGene:   Hs.259831
Chromosome Mapping:   7q22

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