PrimePCR™ ddPCR™ Expression Probe Assay: MLH1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049644; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032951
Chromosome Location:   3:37070305-37081680question
Amplicon Length:   93

Gene Information

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their full-length natures have not been determined.[provided by RefSeq Nov 2009]

Gene Symbol:   MLH1
Gene Name:   mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
Aliases:   COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1
RefSeq:   NC_000003.11 NG_007109.1 NG_008418.1 NT_022517.18
Ensembl:   ENSG00000076242
Entrez:   4292
UniGene:   Hs.195364
Chromosome Mapping:   3p21.3

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