PrimePCR™ ddPCR™ Expression Probe Assay: TSG101, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049612; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032888
Chromosome Location:   11:18502161-18503304question
Amplicon Length:   120

Gene Information

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq Jul 2008]

Gene Symbol:   TSG101
Gene Name:   tumor susceptibility gene 101
Aliases:   TSG10, VPS23
RefSeq:   NC_000011.9 NG_012138.1 NT_009237.18
Ensembl:   ENSG00000074319
Entrez:   7251
UniGene:   Hs.523512
Chromosome Mapping:   11p15

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