PrimePCR™ ddPCR™ Expression Probe Assay: SMC1A, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049584; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032838
Chromosome Location:   X:53440376-53441819question
Amplicon Length:   93

Gene Information

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis although those complexes at the kinetochore remain. Therefore the encoded protein is thought to be an important part of functional kinetochores. In addition this protein interacts with BRCA1 and is phosphorylated by ATM indicating a potential role for this protein in DNA repair. This gene which belongs to the SMC gene family is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq Jul 2008]

Gene Symbol:   SMC1A
Gene Name:   structural maintenance of chromosomes 1A
Aliases:   CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
RefSeq:   NC_000023.10 NG_006988.1 NT_011630.14
Ensembl:   ENSG00000072501
Entrez:   8243
UniGene:   Hs.211602
Chromosome Mapping:   Xp11.22-p11.21

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