PrimePCR™ ddPCR™ Expression Probe Assay: SPA17, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049465; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032624
Chromosome Location:   11:124564434-124564562question
Amplicon Length:   99

Gene Information

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq Jan 2009]

Gene Symbol:   SPA17
Gene Name:   sperm autoantigenic protein 17
Aliases:   CT22, SP17, SP17-1
RefSeq:   NC_000011.9 NG_028132.1 NT_033899.8
Ensembl:   ENSG00000064199
Entrez:   53340
UniGene:   Hs.286233
Chromosome Mapping:   11q24.2

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