PrimePCR™ ddPCR™ Expression Probe Assay: LZTS1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049451; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032601
Chromosome Location:   8:20112478-20112610question
Amplicon Length:   103

Gene Information

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq Nov 2009]

Gene Symbol:   LZTS1
Gene Name:   leucine zipper, putative tumor suppressor 1
Aliases:   F37, FEZ1
RefSeq:   NC_000008.10 NG_015834.1 NT_167187.1
Ensembl:   ENSG00000061337
Entrez:   11178
UniGene:   Hs.521432
Chromosome Mapping:   8p22

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