PrimePCR™ ddPCR™ Expression Probe Assay: TBXAS1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049437; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032574
Chromosome Location:   7:139529257-139572122question
Amplicon Length:   81

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. However this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2 a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis cardiovascular disease and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2008]

Gene Symbol:   TBXAS1
Gene Name:   thromboxane A synthase 1 (platelet)
Aliases:   CYP5, CYP5A1, FLJ52771, GHOSAL, THAS, TS, TXAS, TXS
RefSeq:   NC_000007.13 NG_008422.1 NT_007914.15
Ensembl:   ENSG00000059377
Entrez:   6916
UniGene:   Hs.520757
Chromosome Mapping:   7q34-q35

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