PrimePCR™ ddPCR™ Expression Probe Assay: HERPUD1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049395; exonic

 
Fluorophore:   FAM
List Price:    $207.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032496
Chromosome Location:   16:56973179-56973812question
Amplicon Length:   69

Gene Information

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins the increased expression of proteins involved in polypeptide folding known as the unfolded protein response (UPR) and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   HERPUD1
Gene Name:   homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Aliases:   HERP, KIAA0025, Mif1, SUP
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000051108
Entrez:   9709
UniGene:   Hs.146393
Chromosome Mapping:   16q13

Number Description Download