PrimePCR™ ddPCR™ Expression Probe Assay: AANAT, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040362; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5030629
Chromosome Location:   17:74465279-74465749question
Amplicon Length:   103

Gene Information

The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2009]

Gene Symbol:   AANAT
Gene Name:   aralkylamine N-acetyltransferase
Aliases:   SNAT
RefSeq:   NC_000017.10 NT_010783.15 NG_015976.1
Ensembl:   ENSG00000129673
Entrez:   15
UniGene:   Hs.431417
Chromosome Mapping:   17q25

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