PrimePCR™ ddPCR™ Expression Probe Assay: CCR1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0024565; Exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5026313
Chromosome Location:   3:46245541-46245662question
Amplicon Length:   92

Gene Information

This gene encodes a member of the beta chemokine receptor family which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha) regulated on activation normal T expressed and secreted protein (RANTES) monocyte chemoattractant protein 3 (MCP-3) and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response and susceptibility to virus and parasite. This gene and other chemokine receptor genes including CCR2 CCRL2 CCR3 CCR5 and CCXCR1 are found to form a gene cluster on chromosome 3p. [provided by RefSeq Jul 2008]

Gene Symbol:   CCR1
Gene Name:   chemokine (C-C motif) receptor 1
Aliases:   CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000163823
Entrez:   1230
UniGene:   Hs.301921
Chromosome Mapping:   3p21

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