PrimePCR™ ddPCR™ Expression Probe Assay: PLP1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0024430; Exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5026128
Chromosome Location:   X:103040513-103040644question
Amplicon Length:   102

Gene Information

This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction stabilization and maintenance of myelin sheaths as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs have been identified for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PLP1
Gene Name:   proteolipid protein 1
Aliases:   HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
RefSeq:   NC_000023.10 NT_011651.17 NG_008863.1
Ensembl:   ENSG00000123560
Entrez:   5354
UniGene:   Hs.1787
Chromosome Mapping:   Xq22

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