PrimePCR™ ddPCR™ Expression Probe Assay: KCNJ1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0024253; Exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5025865
Chromosome Location:   11:128708775-128708951question
Amplicon Length:   147

Gene Information

Potassium channels are present in most mammalian cells where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome which is characterized by salt wasting hypokalemic alkalosis hypercalciuria and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   KCNJ1
Gene Name:   potassium inwardly-rectifying channel, subfamily J, member 1
Aliases:   KIR1.1, ROMK, ROMK1
RefSeq:   NC_000011.9 NT_033899.8 NG_009379.1
Ensembl:   ENSG00000151704
Entrez:   3758
UniGene:   Hs.527830
Chromosome Mapping:   11q24

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