PrimePCR™ ddPCR™ Expression Probe Assay: PEG10, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0023986; Exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5025451
Chromosome Location:   7:94292864-94292967question
Amplicon Length:   74

Gene Information

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs) RF1 and RF1/RF2 as well as retroviral-like slippage and pseudoknot elements which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants as well as from use of upstream non-AUG (CUG) start codon have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq May 2010]

Gene Symbol:   PEG10
Gene Name:   paternally expressed 10
Aliases:   EDR, HB-1, KIAA1051, MEF3L, Mar2, Mart2, RGAG3
RefSeq:   NC_000007.13 NG_008893.1 NG_011340.1 NT_007933.15
Ensembl:   ENSG00000242265
Entrez:   23089
UniGene:   Hs.147492
Chromosome Mapping:   7q21

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