PrimePCR™ ddPCR™ Copy Number Assay: MAGI2, Human

PrimePCR

ddPCR probe assay designed for copy number variation analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; 69nt amplicon; intronic; HEX version of MAGI2 (dHsaCP1000173)

 
Fluorophore:   HEX
List Price:    $254.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Copy Number Variation
Unique Assay ID:   dHsaCP2507090
Chromosome Location:   hg197:78131076-78131198question
Amplicon Length:   69
Reference Assays:   , , ,
Restriction Enzymes:   HaeIII

Gene Information

The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains a guanylate kinase-like domain and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq Jul 2008]

Gene Symbol:   MAGI2
Gene Name:   membrane associated guanylate kinase, WW and PDZ domain containing 2
Aliases:   ACVRIP1, AIP1, ARIP1, MAGI-2, SSCAM
RefSeq:   NC_000007.13 NG_011487.1 NT_007933.15
Ensembl:   ENSG00000187391
Entrez:   9863
UniGene:   Hs.603842
Chromosome Mapping:   7q21

  Download Validation Data (.pdf)


Products used to generate validation data:

ddPCR Instrument QX200
ddPCR Supermix ddPCR Supermix for Probes (no dUTP)
Experimental Sample NA18916,AG09394

Copy Number
Copy number analysis of two samples, using the EIF2C1 reference assay. Technical replicates are shown.

Copy Number Text

Copy Number
Copy number analysis of two samples, using the EIF2C1 reference assay. Technical replicates are shown.

Copy Number Text

ddPCR Amplitude Scatter Plot
Single-well data of target assay (FAM, Channel 1) duplexed to EIF2C1 reference assay (HEX, Channel 2).

ddPCR Amplitude Scatter Plot Text

ddPCR Amplitude Scatter Plot
Single-well data of target assay (FAM, Channel 1) duplexed to EIF2C1 reference assay (HEX, Channel 2).

ddPCR Amplitude Scatter Plot Text

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