PrimePCR™ ddPCR™ Copy Number Assay: IL11RA, Human

PrimePCR

ddPCR probe assay designed for copy number variation analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; 63nt amplicon; crosses exon-intron junction; FAM version of IL11RA (dHsaCP2506601)

 
Fluorophore:   FAM
List Price:    $254.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Copy Number Variation
Unique Assay ID:   dHsaCP2500410
Chromosome Location:   hg199:34658416-34658538question
Amplicon Length:   63
Reference Assays:   , , ,
Restriction Enzymes:   HaeIII

Gene Information

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and three variants encoding two different isoforms have been identified. [provided by RefSeq Dec 2008]

Gene Symbol:   IL11RA
Gene Name:   interleukin 11 receptor, alpha
Aliases:   MGC2146
RefSeq:   NC_000009.11 NT_008413.18
Ensembl:   ENSG00000137070
Entrez:   3590
UniGene:   Hs.591088
Chromosome Mapping:   9p13

  Download Validation Data (.pdf)


Products used to generate validation data:

ddPCR Instrument QX200
ddPCR Supermix ddPCR Supermix for Probes (no dUTP)
Experimental Sample NA18916,AG09394

Copy Number
Copy number analysis of two samples, using the EIF2C1 reference assay. Technical replicates are shown.

Copy Number Text

ddPCR Amplitude Scatter Plot
Single-well data of target assay (FAM, Channel 1) duplexed to EIF2C1 reference assay (HEX, Channel 2).

ddPCR Amplitude Scatter Plot Text

Number Description Download