PrimePCR™ ddPCR™ Copy Number Assay: FLT4, Human

PrimePCR

ddPCR probe assay designed for copy number variation analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; 67nt amplicon; exonic; FAM version of FLT4 (dHsaCP2506660)

 
Fluorophore:   FAM
List Price:    $254.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Copy Number Variation
Unique Assay ID:   dHsaCP2500401
Chromosome Location:   hg195:180029741-180029863question
Amplicon Length:   67
Reference Assays:   , , ,
Restriction Enzymes:   HaeIII

Gene Information

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq Jul 2008]

Gene Symbol:   FLT4
Gene Name:   fms-related tyrosine kinase 4
Aliases:   FLT41, LMPH1A, PCL, VEGFR3
RefSeq:   NC_000005.9 NT_023133.13 NG_011536.1
Ensembl:   ENSG00000037280
Entrez:   2324
UniGene:   Hs.646917
Chromosome Mapping:   5q35.3

  Download Validation Data (.pdf)


Products used to generate validation data:

ddPCR Instrument QX200
ddPCR Supermix ddPCR Supermix for Probes (no dUTP)
Experimental Sample NA18916,AG09394

Copy Number
Copy number analysis of two samples, using the EIF2C1 reference assay. Technical replicates are shown.

Copy Number Text

ddPCR Amplitude Scatter Plot
Single-well data of target assay (FAM, Channel 1) duplexed to EIF2C1 reference assay (HEX, Channel 2).

ddPCR Amplitude Scatter Plot Text

Number Description Download