Adeno-associated viruses (AAV) are a common vector for gene therapies and consist of a genome payload inside a capsid shell. During production, empty capsids may be produced that lack a DNA payload, making the ratio of empty-full capsids a key quality attribute.
In this webinar, Dr. Chelsea Pratt will explore the field of gene therapy, highlighting key challenges and the predominant current techniques. She will discuss how a new kit from Bio-Rad can simultaneously measure viral titer, capsid titer and empty-full ratio in AAV samples, empowering and improving gene therapy research.
Attend this webinar to discover:
The importance of understanding empty-full vector ratios in gene therapy development
Common techniques in measuring empty-full AAV titer
A new digital PCR approach to measuring empty-full titer
How new techniques compare to previous methodologies