Using Bioinformatics to Design CRISPR-Based Treatments for Genetic Diseases


The potential for off-target effects is a major factor in ethical discussions involving CRISPR-mediated gene editing technology. Learn how your students can use bioinformatics to design Cas9 target sites in the human genome and evaluate the risk of off-target effects. We'll use free resources that you can incorporate as a capstone activity to your CRISPR gene editing lessons.