Macro-Prep CM Media

print email

Macro-Prep CM weak cation exchange support meets the demands of analytical, semipreparative, and process-scale applications. This rigid, macroporous hydrophilic support provides exceptional capacity, resolution, and throughput in a chemically and mechanically stable form. Macro-Prep CM operates well at low and medium pressures and exhibits minimal volume changes in response to variations in pH or ionic strength. It provides consistent and reproducible results. Advantages of Macro-Prep CM support include:

High capacity for biomolecules
High resolution of complex biological mixtures
Rigid polymer matrix that allows high flow rates at moderate pressures
Hydrophilic matrix that reduces nonspecific binding
Macroporous beads that enhance access to ionic sites
Chemical, mechanical, and thermal stability

Type of ion exchanger	Weak cation
Counterion	Na⁺
Total ionic capacity	210±40 µeq/ml
Median particle	50 µm
Storage solution	20% ethanol
Recommended maximum linear flow rate	3,000 cm/hr
Chemical stability
1% SDS, 24 hr	Yes
6 M guanidine-HCl, 24 hr	Yes
pH stability	1–12
Volume changes
pH 4–10	<1%
0.1–1.0 M NaCl	<4%
Regeneration	1 M NaCl
Autoclavability (121°C, 30 min)	Yes