Bio-Scale Mini Macro-Prep High S cartridges are available in 1 and 5 ml sizes. These cartridges come prepacked with Macro-Prep High S strong cation exchange media and are ideal for method scouting and small-scale purifications.
Macro-Prep High S media contain sulfonate functional groups and are ideal for purifying basic and neutral proteins and peptides. The support is an excellent choice for rapid purification and meets the demands of analytical, semipreparative, and process-scale applications. This methacrylate copolymer bead provides high-resolution separations at very high flow rates. Changes in pH or ionic strength of the buffer do not cause shrinking or swelling of the support. Macro-Prep High S can be sanitized with chaotropic agents and can be autoclaved. It provides consistent and reproducible results.
Advantages of Macro-Prep High S include:
- High capacity for biomolecules
- High resolution of complex biological mixtures
- Rigid polymer matrix that allows high flow rates at moderate pressures
- Hydrophilic matrix that reduces nonspecific binding
- Macroporous beads that enhance access to ionic sites
- High chemical, mechanical, and thermal stability
Bio-Scale Mini cartridges have a polypropylene double-wall construction* that provides extra durability and allows easy, reliable runs at pressures up to 45 psi with the aqueous buffers most commonly used for protein separation. Bio-Scale Mini cartridges are ideal for low-pressure chromatography applications. Luer fittings make connections simple; adaptors are available to allow connection to all types of chromatography systems.
Regulatory support files are available upon request. Bio-Rad Laboratories is an ISO 9001-registered corporation.
* U.S. Patent 7,208,087.