Analytical Grade Anion Exchange Media



AG, AG-MP, and Bio-Rex 5 Resins

AG (analytical grade) resins — AG resins are extensively purified to remove both organic and inorganic impurities. Resins are sized to consistently give narrow wet mesh ranges, which provide high resolution and excellent reproducibility. AG resins are available as both strong and weak cation and anion exchangers and as mixed-bed ion exchangers. Many are available in several ionic forms and can be converted from one form to another. AG resins are primarily used for the separation of low molecular weight compounds such as inorganic ions, organic acids, nucleic acids, or carbohydrates.

AG 1 and 2 resins are strongly basic anion exchangers with quaternary ammonium functional groups attached to the styrene divinylbenzene copolymer lattice. The amount of resin crosslinkage determines the bead pore size. A resin with a lower percentage of crosslinkage has a more open structure permeable to higher molecular weight substances than a highly crosslinked resin. It also has a lower physical resistance to shrinking and swelling, so that it absorbs more water and swells to a larger wet diameter than highly crosslinked resin of equivalent dry diameter. The lowered crosslinked resins, such as AG 1-X2, are useful for the sorption and fractionation of relatively high molecular weight substances such as peptides, ribo- and deoxyribonucleotides, and uranium. The higher crosslinked resins, such as AG 1-X8, are used for sorption, exchange, and separation of low molecular weight inorganic anions, and in applications such as cyclic nucleotide assays and fractionation of organic acids.

AG MP-1M resin — this resin is the macroporous equivalent of AG 1 resin. Its effective surface area approximates 23 square meters per dry gram, 20% porosity.

Bio-Rex 5 resins — contain primarily tertiary, but also some quaternary, amines on a styrene divinylbenzene lattice. Bio-Rex 5 resins exchange anions, such as iodide, bromide, and chloride, with weak interactions, allowing easy elution and regeneration. Bio-Rex 5 resins have an affinity for organic acids that can be used to remove acids from sugars. It is available in two dry mesh sizes (100–200 and 200–400) and are all analytical grade purity. They have been exhaustively sized, purified, and converted to make them suitable for accurate, reproducible analytical techniques.

Molecular Biology and Biotechnology Grade Resins

Molecular biology grade resins, chemically identical to the equivalent analytical grade resins, are certified to be free of endo- and exonuclease activity and ligase inhibitors.

Biotechnology grade resins have undergone special processing and contain fewer than 100 microorganisms/g.

Larger volumes and special packaging for industrial applications are available on request.