VARIANT™ Sickle Cell Short Program
Product Highlights
- Unequivocal chromatographic results
- Rapid, 3-minute analysis
- Walkaway operation
- “Smart” reports highlight detected hemoglobins, area percentages and other key sample data
- Proven, reliable HPLC technology
- Electronic data – interfaces with any lab information system
Which Would You Rather Read?
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1. Isoelectric Focusing
- Labor intensive
- Subjective interpretation
- Multiple-step sample preparation
- Can require multiple reviewers for 1 result
- Manual data entry
- Hazardous chemicals
| 2. VARIANT Sickle Cell Short Program - Automated processing
- Objective analysis
- One-step sample preparation
- Printed record
- Electronic record transfer
- Better patient sample tracking
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Clinical Background
Sickle cell anemia is a disease caused by a genetic mutation in the β-globin generesulting in the production of hemoglobin S instead of hemoglobin A. In this condition, oxygen-carrying red blood cells quickly lose their ability to carry oxygen throughout the body. The cells tend to distort and elongate, which causes them to become rigid and assume a sickle-shape. Over time, the sickle-shaped cells cause obstructions to blood microcirculation, resulting in tissue damage and other life threatening complications.