VARIANT Sickle Cell Short Program Reorder Pack

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Overview

Results and Background
VARIANT™ Sickle Cell Short Program

VARIANT™ Sickle Cell Short Program

Product Highlights

  • Unequivocal chromatographic results
  • Rapid, 3-minute analysis
  • Walkaway operation
  • “Smart” reports highlight detected hemoglobins, area percentages and other key sample data
  • Proven, reliable HPLC technology
  • Electronic data – interfaces with any lab information system

Which Would You Rather Read?


1. Isoelectric Focusing

  • Labor intensive
  • Subjective interpretation
  • Multiple-step sample preparation
  • Can require multiple reviewers for 1 result
  • Manual data entry
  • Hazardous chemicals


2. VARIANT Sickle Cell Short Program

  • Automated processing
  • Objective analysis
  • One-step sample preparation
  • Printed record
  • Electronic record transfer
  • Better patient sample tracking

Clinical Background

Sickle cell anemia is a disease caused by a genetic mutation in the β-globin generesulting in the production of hemoglobin S instead of hemoglobin A. In this condition, oxygen-carrying red blood cells quickly lose their ability to carry oxygen throughout the body. The cells tend to distort and elongate, which causes them to become rigid and assume a sickle-shape. Over time, the sickle-shaped cells cause obstructions to blood microcirculation, resulting in tissue damage and other life threatening complications.

The VARIANT Sickle Cell Short Program Reorder Pack provides detection and presumptive identification of hemoglobins S, F, A, C, D, and E in dried blood spot specimens from newborns. Rapid analysis and unattended operation maximize productivity and efficiency.

  • Increased productivity: The 3-minute specimen analysis delivers unattended high throughput for your laboratory

  • Objectivity: Hemoglobins S, F, A, C, D, and E are detected based on quantitative thresholds. Patient data can be easily stored off-line on the laboratory’s information management system

  • Relative ratios: Relative ratios between different hemoglobins can help distinguish sickle cell disease (FS) from sickle cell trait (FAS) and sickle/β-thalassemia (FSA)
VARIANTnbs Sickle Cell Program Reorder Pack

250-3000
Reagents, supplies for 1000 hemoglobin S, F, A, C, D, E tests of newborn dried blood using VARIANTnbs System; aids detection of abnormal hemoglobin

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