Apoptosis 関連アッセイ

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Bio-Plex Pro RBM Apoptosis Assays

Overview

Available Bio-Plex Pro™ Apoptosis Assays
Apoptosis Panel 1 Apoptosis Panel 2 Apoptosis Panel 3
Analyte Bead Region Analyte Bead Region Analyte Bead Region
Bak 74 Bad 74 Active caspase-3 57
Bax 27 Bax/Bcl-2 dimer 42 Bcl-xL/Bak dimer 47
Lamin B, intact and
45 kD
14 Bcl-xL 22 Mcl-1/Bak dimer 54
Smac 19 Bim 12 Survivin 20
  Mcl-1 18  

 

Apoptosis Analyte Descriptions
Analyte Analyte Descriptions Apoptotic Action Apoptotic Cell
Bak Bcl-homologous antagonist/killer is a pro-apoptotic member of the Bcl-2 family. In healthy cells, it is integrated in the mitochondrial outer membrane. Upon apoptotic stimuli, Bak forms oligomer channels in the mitochondrial membrane for cytochrome C release. This activity is regulated by forming a complex with anti-apoptotic Mcl-1 and Bcl-xL. Pro-apoptotic Mitochondrial membrane
Bax Bcl-2 associated protein X is a pro-apoptotic member of the Bcl-2 family. In healthy cells, it is found as a monomer in the cytosol, but upon apoptotic stimuli, it translocates to the mitochondrial outer membrane and forms large oligomeric complexes. There it interacts with pore proteins to enable cytochrome C release into the cytosol and initiate the caspase activation pathway for apoptosis. Bax may cycle to the mitochondrial membrane and dimerize with Bcl-xL. Pro-apoptotic Moves to the mitochondrial membrane
Lamin B,
intact and 45 kD
Nuclear lamins are proteins of intermediate filament type located at the outer rim of the nucleus. They consist of two types of polypeptides, lamin A and lamin B. Lamin B consists of B1 and B2 subtypes. Lamins mechanically stabilize the cell nucleus and also play a role in DNA replication and chromatin organization. Lamin B is cleaved by caspase-3 and caspase-6 during the early phases of apoptosis (up to 90 min) before DNA fragmentation. Detection of cytoplasmic dissociated lamin B indicates cell apoptosis. Early indicator of apoptosis Cytosol
Smac Second mitochondria-derived activator of caspase is a dimeric mitochondrial protein synthesized in the cytoplasm as a 239 amino acid precursor protein, with 55 amino acids at the N-terminus serving as a mitochondrial-targeting sequence. Under apoptotic stimuli, it is proteolytically cleaved to a 23 kD active form and released into the cytosol together with cytochrome C, where it reverses IAP inhibition of caspase-9, allowing caspase-9 to activate the caspase cascade. Pro-apoptotic Cytosol
Bad Bcl-2-associated death promoter is a pro-apoptotic, BH3-only binding domain member of the Bcl-2 family. BH3-only proteins connect apoptotic death signals to the activation of Bax and Bak, which control mitochondrial membrane disruption and apoptosis. Phosphorylated BAD (pBAD) is typically bound to the cytosolic protein 14-3-3, and is thus sequestered away from the mitochondria. Dephosphorylation results in the release of cytosolic (free) BAD, which binds to and inhibits the pro-survival activity of Bcl-2 family proteins at the mitochondrial membrane. Pro-apoptotic Cytosol (free)
Bax/Bcl-2 dimer B-cell lymphoma-2 is an anti-apoptotic protein that resides on the outer mitochondrial membrane. When bound to Bax as a heterodimer, it inhibits permeability of the mitochondrial membrane, preventing release of cytochrome C. Anti-apoptotic Mitochondrial membrane; decreased with apoptosis
Bcl-xL B-cell lymphoma-extra large is an anti-apoptotic member of the Bcl-2 family found in the outer mitochondrial membrane. Heterodimerization with pro-apoptotic proteins (especially Bak) inhibits apoptosis by preventing release of cytochrome C. Anti-apoptotic Mitochondrial membrane
Bim Bcl-2-interacting mediator of cell death is a pro-apoptotic protein belonging to the BH3-only group of the Bcl-2 family. Bim binds and antagonizes pro-survival members of the Bcl-2 family such as Mcl-1, Bcl-xL, and Bcl-2. Three prominent isoforms are generated by alternative splicing: Bim-S, Bim-L, and Bim-EL. Each isoform has the ability to induce apoptosis. Pro-apoptotic Cytosol or mitochodrial membrane if dimerized
Mcl-1 Induced myeloid leukemia cell differentiation protein-1 is an anti-apoptotic member of the Bcl-2 family. Heterodimerization with pro-apoptotic proteins (especially Bak) inhibits apoptosis. While Mcl-1 may not be as potent a protector against apoptosis as Bcl-2, it does appear to be the main anti-apoptotic protein in some cell types, including neutrophils. Anti-apoptotic Mainly mitochondrial membrane, some in cytosol
Active Caspase-3 Cysteinyl aspartyl protease-3 belongs to the peptidase C14A enzyme family and is known to play an important role in the apoptotic cascade. The active enzyme is formed by cleavage of the inactive 32 kD pro-enzyme into the p17 and p12 subunits. Two of each subunit noncovalently heterodimerize, giving the final enzyme two catalytic sites. Active caspase-3 cleaves and activates other caspases and is a primary regulator of apoptotic-associated proteolysis. Pro-apoptotic Cytosol (high levels)
Bcl-xL/Bak dimer Anti-apoptotic Bcl-xL heterodimerizes with Bak at the mitochondrial outer membrane and inhibits permeability of the mitochondrial membrane, preventing release of cytochrome C. During apoptosis BH3-only proteins, such as Bim and Bad, will bind to Bcl-xL and cause Bak to be released. Upon release, Bak will oligomerize creating pores in the mitochondrial membrane. Anti-apoptotic Mitochondrial membrane; decreased with apoptosis
Mcl-1/Bak dimer Anti-apoptotic Mcl-1 heterodimerzes with Bax and Bak at the mitochondrial outer membrane to prevent their activation, thus inhibiting cytochrome C release from the mitochondria. Anti-apoptotic Mitochondria; decreased with apoptosis
Survivin Survivin is a 16 kD member of the Inhibitor of Apoptosis (IAP) family, which also plays a role in chromosome segregation and cytokinesis. The anti-apoptotic function of survivin comes from its ability to inhibit the activation of caspases-3 and -7. Survivin is found to be upregulated in various tumors. Anti-apoptotic Cytosol/nucleus
Apoptosis Signaling Pathway

Apoptosis Signaling Pathway

Apoptosis is induced by at least two distinct signaling pathways, extrinsic and intrinsic. The extrinsic pathway is triggered by signaling through death receptors such as Fas, followed by downstream activation of caspase-8 and caspase-3. The intrinsic pathway is triggered by cytotoxic stress, which leads to translocation of Bcl-2 family proteins, Bax and Bak, to the mitochondrial membrane. Oligomerization of Bax and Bak causes release of cytochrome C into the cytosol, which promotes apoptosome formation, caspase activation, degradation of nuclear Lamin B, and cell death. Pro-apoptotic proteins included in the panels (); Anti-apoptotic proteins included in the panels (); Proteins involved in apoptosis but not included in the panels ().

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Bio-Plex Pro RBM apoptosis アッセイキットは、細胞および組織のLysateサンプルを用い、アポトーシス関連因子を検出するためにデザインされています。キットは3種類のパネルで構成されおり、一般的なannexin Vアッセイの代わり、もしくは補完する方法として使用することが可能です。BakやBcl-2、カスパーゼアッセイを含む内在性のパスウェイによるプログラムされた細胞死への関連、兆候、誘導に関連する一連の細胞内タンパク質が含まれます。

 パネル1 測定項目:
  • Bak
  • Bax
  • Lamin B
  • Smac
パネル2 測定項目:
  • Bad
  • Bax/Bcl-2 dimer
  • Bcl-xL
  • Bim
  • Mcl-1
パネル3測定項目:
  • Active caspase-3
  • Bcl-xL/Bak dimer
  • Mcl-1/Bak dimer
  • Survivin

特長

  • 高精度 および 高いLot 間の再現性
  • 磁気ビーズ採用
  • 2段階のクオリティコントロール

キットの構成

  • 抗体付磁気ビーズ
  • 検出抗体
  • スタンダード
  • 2段階のコントロール
  • スタンダード希釈液
  • ブロッキングバッファー
  • Lysate希釈バッファー(LDB)
  • サイトゾル抽出バッファー(CEB)
  • 10x アッセイバッファー
  • 10x ストレプトアビジン-PE
  • フラットボトムプレート
  • シーリングテープ

対応パッケージ

  • プレミックスパネル

※カスタムパネル、シングルプレックスセット、スタンダードの単品販売はございません。

測定対応機種

More Information

より詳細な情報は以下をご参照ください。

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Bio-Plex Pro RBM Apoptosis 1 4-Plexパネル

171WAR1CK
抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ

171WAR1CK /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-RBM-Apoptosis-Assays/171-WAR1CK_1378746542.xml 171WAR1CK 09/09/13 09:54 AM N ja_JP 09/11/23 10:03 AM true Done internet/product_SKU JP LSR 2017-10-27 13:55:05 171war1ck-bio-plex-pro-rbm-apoptosis-panel-1 171WAR1CK Bio-Plex Pro RBM Apoptosis Panel 1 Bio-Plex Pro RBM Apoptosis 1 4-Plexパネル 抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ 1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 4 apoptosis markers in cell and tissue lysates /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/bio-plex-pro-rbm-apoptosis-panel-1-171-war1ck-thumb.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/bio-plex-pro-rbm-apoptosis-panel-1-171-war1ck.jpg preview Karen Moss Bio-Plex Pro RBM Apoptosis Panel 1 抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ 09/09/13 09:54 AM 09/11/23 10:03 AM JP ja LSR /ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-RBM-Apoptosis-Assays N 0 <p><strong>Bio-Plex Pro RBM Apoptosis 1 パネル</strong> は、 内在性パスウェイによるアポトーシスとの関連性、兆候、誘導に関わる細胞内タンパク質の検出のために使用することができます。</p> <h2 class="descHeader">測定項目</h2> <ul> <li>Bak</li> <li>Bax</li> <li>Lamin B</li> <li>Smac</li> </ul> <h2 class="descHeader">対応サンプル</h2> <ul> <li>Cell lysates</li> <li>組織 lysates</li> </ul> <h2 class="descHeader">特長</h2> <ul> <li>高精度 および 高いLot間の再現性 </li> <li>磁気ビーズ採用 </li> <li>2段階のクオリティコントロール </li> </ul> <h2 class="descHeader">キットの構成</h2> <table border="0" cellspacing="0" cellpadding="0" width="500"> <tbody> <tr> <td valign="top"> <ul style="margin-left:-25px"> <li>抗体付磁気ビーズ</li> <li>検出抗体</li> <li>スタンダード</li> <li>2段階のコントロール</li> <li>スタンダード希釈液</li> <li>ブロッキングバッファー</li> <li>Lysate希釈バッファー(LDB) </li> </ul> </td> <td valign="top"> <ul style="margin-left:-25px"> <li>サイトゾル抽出バッファー(CEB) </li> <li>10x アッセイバッファー </li> <li>10x ストレプトアビジン-PE</li> <li>フラットボトムプレート </li> <li>シーリングテープ </li> </ul> </td> </tr> </tbody> </table> <h2 class="descHeader">他のApoptosisパネル</h2> <p><a href="/ja-jp/product/bio-plex-pro-rbm-apoptosis-assays">Bio-Plex Pro RBM Apoptosisパネル</a>は3種類あり、詳細な内在性パスウェイの測定が可能です。</p> <ul> <li>パネル1 (171-WAR1CK) 測定項目: Bak, Bax, Lamin B, Smac</li> <li>パネル2 (<a href="/evportal/destination/commerce/sku_detail?cmd=catProductDetail&amp;vertical=LSR&amp;productID=171-WAR2CK">171-WAR2CK</a>) 測定項目: Bad, Bax/Bcl-2 dimer, Bcl-xL, Bim, Mcl-1</li> <li>パネル3 (<a href="/evportal/destination/commerce/sku_detail?cmd=catProductDetail&amp;vertical=LSR&amp;productID=171-WAR3CK">171-WAR3CK</a>) 測定項目: Active caspase-3, Bcl-xL/Bak dimer, Mcl-1/Bak dimer, Survivin</li> </ul> <h2 class="descHeader">測定対応機種</h2> <ul> <li><a href="/ja-jp/product/bio-plex-reader-tools/bio-plex-magpix-multiplex-reader">Bio-Plex MAGPIX もしくは Luminex MAGPIX システム</a></li> <li><a href="/ja-jp/product/bio-plex-200-systems">Bio-Plex 200 もしくは Luminex 200 システム</a></li> <li><a href="/ja-jp/product/bio-plex-3d-suspension-array-system">Bio-Plex 3D もしくは FLEXMAP 3D システム</a></li> </ul> <h2 class="descHeader">詳細情報</h2> <p>より詳細な情報は以下をご参照ください。</p> <ul> <li><a href="/webroot/web/pdf/lsr/literature/bulletin_6474.pdf" target="_blank">Product information sheet</a></li> <li><a href="/webroot/web/pdf/lsr/literature/10033631.pdf" target="_blank">Instruction manual</a></li> <li><a href="/webroot/web/pdf/lsr/literature/10033632.pdf" target="_blank">Quick guide</a></li> <li><a href="/webroot/web/pdf/lsr/literature/Bulletin_6159.pdf">Cancer panels product information sheet </a></li> <li><a href="/webroot/web/pdf/lsr/literature/Bulletin_6285.pdf">Cell signaling product information sheet </a></li> </ul> /webroot/web/html/lsr/japan/japanese/products/bioplex_suspension_array/sku_view/description bio-plex-pro-rbm-apoptosis-panel-1-171-war1ck-desc.html /webroot/web/html/lsr/japan/japanese/products/bioplex_suspension_array/sku_view/description/bio-plex-pro-rbm-apoptosis-panel-1-171-war1ck-desc.html 1 0 false false false /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR1CK&CartQuote=QT&quantity= 1367 false true false ¥250,000 false null /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR1CK&AddToDefaultWishList=true&quantity= false false true 41105300 true false true false true /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR1CK&quantity= 171WAR1CK
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Bio-Plex Pro RBM Apoptosis 2 5-Plexパネル

171WAR2CK
抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ

171WAR2CK /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-RBM-Apoptosis-Assays/171-WAR2CK_1378747475.xml 171WAR2CK 09/09/13 10:23 AM N ja_JP 09/11/23 10:24 AM true Done internet/product_SKU JP LSR 2017-10-27 13:55:05 171war2ck-bio-plex-pro-rbm-apoptosis-panel-2 171WAR2CK Bio-Plex Pro RBM Apoptosis Panel 2 Bio-Plex Pro RBM Apoptosis 2 5-Plexパネル 抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ 1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 5 apoptosis markers in cell and tissue lysates /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/bio-plex-pro-rbm-apoptosis-panel-2-171-war2ck-thumb.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/bio-plex-pro-rbm-apoptosis-panel-2-171-war2ck.jpg preview Karen Moss 09/09/13 10:23 AM 09/11/23 10:24 AM JP ja LSR /ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-RBM-Apoptosis-Assays N 0 <p><strong>Bio-Plex Pro RBM Apoptosis 2 パネル</strong>は、 内在性パスウェイによるアポトーシスとの関連性、兆候、誘導に関わる細胞内タンパク質の検出のために使用することができます。</p> <h2 class="descHeader">測定項目</h2> <ul> <li>Bad</li> <li>Bax/Bcl-2 dimer</li> <li>Bcl-xL</li> <li>Bim</li> <li>Mcl-1</li> </ul> <ul> </ul> <h2 class="descHeader">対応サンプル</h2> <ul> <li>Cell lysates</li> <li>組織 lysates</li> </ul> <h2 class="descHeader">特長</h2> <ul> <li>高精度 および 高いLot間の再現性 </li> <li>磁気ビーズ採用 </li> <li>2段階のクオリティコントロール </li> </ul> <h2 class="descHeader">キットの構成</h2> <table border="0" cellspacing="0" cellpadding="0" width="500"> <tbody> <tr> <td valign="top"> <ul style="margin-left:-25px"> <li>抗体付磁気ビーズ</li> <li>検出抗体</li> <li>スタンダード</li> <li>2段階のコントロール</li> <li>スタンダード希釈液</li> <li>ブロッキングバッファー</li> <li>Lysate希釈バッファー(LDB) </li> </ul> </td> <td valign="top"> <ul style="margin-left:-25px"> <li>サイトゾル抽出バッファー(CEB) </li> <li>10x アッセイバッファー </li> <li>10x ストレプトアビジン-PE</li> <li>フラットボトムプレート </li> <li>シーリングテープ </li> </ul> </td> </tr> </tbody> </table> <h2 class="descHeader">他のApoptosisパネル</h2> <p><a href="/ja-jp/product/bio-plex-pro-rbm-apoptosis-assays">Bio-Plex Pro RBM Apoptosisパネル</a>は3種類あり、詳細な内在性パスウェイの測定が可能です。</p> <ul> <li>パネル1 (<a href="/evportal/destination/commerce/sku_detail?cmd=catProductDetail&amp;vertical=LSR&amp;productID=171-WAR1CK">171-WAR1CK</a>) 測定項目: Bak, Bax, Lamin B, Smac</li> <li>パネル2 (171-WAR2CK) 測定項目: Bad, Bax/Bcl-2 dimer, Bcl-xL, Bim, Mcl-1</li> <li>パネル3 (<a href="/evportal/destination/commerce/sku_detail?cmd=catProductDetail&amp;vertical=LSR&amp;productID=171-WAR3CK">171-WAR3CK</a>) 測定項目: Active caspase-3, Bcl-xL/Bak dimer, Mcl-1/Bak dimer, Survivin</li> </ul> <h2 class="descHeader">測定対応機種</h2> <ul> <li><a href="/ja-jp/product/bio-plex-reader-tools/bio-plex-magpix-multiplex-reader">Bio-Plex MAGPIX もしくは Luminex MAGPIX システム</a></li> <li><a href="/ja-jp/product/bio-plex-200-systems">Bio-Plex 200 もしくは Luminex 200 システム</a></li> <li><a href="/ja-jp/product/bio-plex-3d-suspension-array-system">Bio-Plex 3D もしくは FLEXMAP 3D システム</a></li> </ul> <h2 class="descHeader">詳細情報</h2> <p>より詳細な情報は以下をご参照ください。</p> <ul> <li><a href="/webroot/web/pdf/lsr/literature/bulletin_6474.pdf" target="_blank">Product information sheet</a></li> <li><a href="/webroot/web/pdf/lsr/literature/10033631.pdf" target="_blank">Instruction manual</a></li> <li><a href="/webroot/web/pdf/lsr/literature/10033632.pdf" target="_blank">Quick guide</a></li> <li><a href="/webroot/web/pdf/lsr/literature/Bulletin_6159.pdf">Cancer panels product information sheet </a></li> <li><a href="/webroot/web/pdf/lsr/literature/Bulletin_6285.pdf">Cell signaling product information sheet </a></li> </ul> /webroot/web/html/lsr/japan/japanese/products/bioplex_suspension_array/sku_view/description bio-plex-pro-rbm-apoptosis-panel-2-171-war2ck-desc.html /webroot/web/html/lsr/japan/japanese/products/bioplex_suspension_array/sku_view/description/bio-plex-pro-rbm-apoptosis-panel-2-171-war2ck-desc.html 1 0 false false false /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR2CK&CartQuote=QT&quantity= 1367 false true false ¥280,000 false null /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR2CK&AddToDefaultWishList=true&quantity= false false true 41105300 true false true false true /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR2CK&quantity= 171WAR2CK
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Bio-Plex Pro RBM Apoptosis 3 4-Plexパネル

171WAR3CK
抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ

171WAR3CK /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-RBM-Apoptosis-Assays/171-WAR3CK_1378747561.xml 171WAR3CK 09/09/13 10:24 AM N ja_JP 09/11/23 10:25 AM true Done internet/product_SKU JP LSR 2017-10-27 13:55:05 171war3ck-bio-plex-pro-rbm-apoptosis-panel-3 171WAR3CK Bio-Plex Pro RBM Apoptosis Panel 3 Bio-Plex Pro RBM Apoptosis 3 4-Plexパネル 抗体付磁気ビーズ、検出抗体、スタンダード、コントロール、スタンダード希釈液、バッファー、ストレプトアビジン-PE、フラットボトムプレート、シーリングテープ 1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard dilluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 4 apoptosis markers in cell and tissue lysates /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/bio-plex-pro-rbm-apoptosis-panel-3-171-war3ck-thumb.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/bio-plex-pro-rbm-apoptosis-panel-3-171-war3ck.jpg preview Karen Moss 09/09/13 10:24 AM 09/11/23 10:25 AM JP ja LSR /ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-RBM-Apoptosis-Assays N 0 <p><strong>Bio-Plex Pro RBM Apoptosis 3 パネル</strong>は、 内在性パスウェイによるアポトーシスとの関連性、兆候、誘導に関わる細胞内タンパク質の検出のために使用することができます。</p> <h2 class="descHeader">測定項目</h2> <ul> <li> Active caspase-3</li> <li>Bcl-xL/Bak dimer</li> <li>Mcl-1/Bak dimer</li> <li>Survivin</li> </ul> <ul> </ul> <h2 class="descHeader">対応サンプル</h2> <ul> <li>Cell lysates</li> <li>組織 lysates</li> </ul> <h2 class="descHeader">特長</h2> <ul> <li>高精度 および 高いLot間の再現性 </li> <li>磁気ビーズ採用 </li> <li>2段階のクオリティコントロール </li> </ul> <h2 class="descHeader">キットの構成</h2> <table border="0" cellspacing="0" cellpadding="0" width="500"> <tbody> <tr> <td valign="top"> <ul style="margin-left:-25px"> <li>抗体付磁気ビーズ</li> <li>検出抗体</li> <li>スタンダード</li> <li>2段階のコントロール</li> <li>スタンダード希釈液</li> <li>ブロッキングバッファー</li> <li>Lysate希釈バッファー(LDB) </li> </ul> </td> <td valign="top"> <ul style="margin-left:-25px"> <li>サイトゾル抽出バッファー(CEB) </li> <li>10x アッセイバッファー </li> <li>10x ストレプトアビジン-PE</li> <li>フラットボトムプレート </li> <li>シーリングテープ </li> </ul> </td> </tr> </tbody> </table> <h2 class="descHeader">他のApoptosisパネル</h2> <p><a href="/ja-jp/product/bio-plex-pro-rbm-apoptosis-assays">Bio-Plex Pro RBM Apoptosisパネル</a>は3種類あり、詳細な内在性パスウェイの測定が可能です。</p> <ul> <li>パネル1 (<a href="/evportal/destination/commerce/sku_detail?cmd=catProductDetail&amp;vertical=LSR&amp;productID=171-WAR1CK">171-WAR1CK</a>) 測定項目: Bak, Bax, Lamin B, Smac</li> <li>パネル2 (<a href="/evportal/destination/commerce/sku_detail?cmd=catProductDetail&amp;vertical=LSR&amp;productID=171-WAR2CK">171-WAR2CK</a>) 測定項目: Bad, Bax/Bcl-2 dimer, Bcl-xL, Bim, Mcl-1</li> <li>パネル3 (171-WAR3CK) 測定項目: Active caspase-3, Bcl-xL/Bak dimer, Mcl-1/Bak dimer, Survivin</li> </ul> <h2 class="descHeader">測定対応機種</h2> <ul> <li><a href="/ja-jp/product/bio-plex-reader-tools/bio-plex-magpix-multiplex-reader">Bio-Plex MAGPIX もしくは Luminex MAGPIX システム</a></li> <li><a href="/ja-jp/product/bio-plex-200-systems">Bio-Plex 200 もしくは Luminex 200 システム</a></li> <li><a href="/ja-jp/product/bio-plex-3d-suspension-array-system">Bio-Plex 3D もしくは FLEXMAP 3D システム</a></li> </ul> <h2 class="descHeader">詳細情報</h2> <p>より詳細な情報は以下をご参照ください。</p> <ul> <li><a href="/webroot/web/pdf/lsr/literature/bulletin_6474.pdf" target="_blank">Product information sheet</a></li> <li><a href="/webroot/web/pdf/lsr/literature/10033631.pdf" target="_blank">Instruction manual</a></li> <li><a href="/webroot/web/pdf/lsr/literature/10033632.pdf" target="_blank">Quick guide</a></li> <li><a href="/webroot/web/pdf/lsr/literature/Bulletin_6159.pdf">Cancer panels product information sheet </a></li> <li><a href="/webroot/web/pdf/lsr/literature/Bulletin_6285.pdf">Cell signaling product information sheet </a></li> </ul> /webroot/web/html/lsr/japan/japanese/products/bioplex_suspension_array/sku_view/description bio-plex-pro-rbm-apoptosis-panel-3-171-war3ck-desc.html /webroot/web/html/lsr/japan/japanese/products/bioplex_suspension_array/sku_view/description/bio-plex-pro-rbm-apoptosis-panel-3-171-war3ck-desc.html 1 0 false false false /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR3CK&CartQuote=QT&quantity= 1367 false true false null false null /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR3CK&AddToDefaultWishList=true&quantity= false false true 41105300 true false true false true /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171WAR3CK&quantity= 171WAR3CK
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Bio-Plex用フィルタープレート

171304502
リッド、トレイ付 96wellx1プレート
吸引式洗浄装置用プレート

171304502 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Disease-Research-/171-304502_1316623295.xml 171304502 09/21/11 09:38 AM N ja_JP 09/21/21 09:38 AM true Done internet/product_SKU JP LSR 2017-10-27 13:55:00 171304502-filter-plate 171304502 Filter Plate Bio-Plex用フィルタープレート リッド、トレイ付 96wellx1プレート<br>吸引式洗浄装置用プレート Pkg of 1, 96-well plate, with clear plastic lid and tray, for Bio-Plex Assays using the vacuum wash method, sealing tape not included /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/171-304502_tn.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/171-304502_view.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_feature/global/171-304502_feature.jpg Karen Moss Bio-Plex用フィルタープレート リッド、トレイ付 96wellx1プレート、吸引式洗浄装置用プレート 171304502, filter, plate, vacuum, wash, method, bio-plex, bioplex, multiplex, singleplex, assays, assay, immunoassay, coupled, magnetic, beads, detection 09/21/11 09:38 AM 09/21/21 09:38 AM JP ja LSR /ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Disease-Research- N 0 &nbsp; 1 0 false false false /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171304502&CartQuote=QT&quantity= 1490 false true false ¥5,000 false null /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171304502&AddToDefaultWishList=true&quantity= false false true 41116100 true false true false true /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171304502&quantity= 171304502
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Bio-Plex Handheld Magnetic Washer

171020100
磁気ビーズ専用マニュアル式洗浄装置
対応プレート:フラットボトムプレート

171020100 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/171-020100_1326308046.xml 171020100 10/29/12 04:16 AM N ja_JP 10/29/22 04:17 AM true Done internet/product_SKU JP LSR 2017-10-27 13:55:00 171020100-bio-plex-handheld-magnetic-washer 171020100 Bio-Plex Hand Held Magnetic Washer Bio-Plex Handheld Magnetic Washer 磁気ビーズ専用マニュアル式洗浄装置<br> 対応プレート:フラットボトムプレート Bio-Plex Handheld Magnetic Washer 1個 /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/171-020100_tn.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/171-020100_view.jpg hbratti Bio-Plex Handheld Magnetic Washer 磁気ビーズ専用マニュアル式洗浄装置<br> 対応プレート:フラットボトムプレート 10/29/12 04:16 AM 10/29/22 04:17 AM JP ja LSR /ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments N 0 1 0 false false false /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171020100&CartQuote=QT&quantity= 1492 false true false ¥120,000 false null /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171020100&AddToDefaultWishList=true&quantity= false false true 41115800 true false true false true /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171020100&quantity= 171020100
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Bio-Plex用フラットボトムプレート

171025001
96well x40プレート
磁気ビーズに対応した洗浄装置用(Bio-Plex Pro Wash StationもしくはHandHeld Magnetic Washer)プレート

171025001 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml 171025001 /default/main/bio-rad/WORKAREA/default 09/21/09 12:07 PM en_US jthvld0m 2017-10-27 13:55:02 true Done internet/product_SKU jthvld0m templatedata/internet/product_SKU/data/ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml LSR 2019-04-06 02:34:48 /default/main/bio-rad/STAGING N /default/main/bio-rad ja_JP 12/31/37 11:59 PM JP 2019-04-06 02:34:48 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml templatedata/internet/product_SKU/data/ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml 171025001-bio-plex-pro-flat-bottom-plates 171025001 Bio-Plex Pro Flat Bottom Plates Bio-Plex用フラットボトムプレート 96well x40プレート<br> 磁気ビーズに対応した洗浄装置用(Bio-Plex Pro Wash StationもしくはHandHeld Magnetic Washer)プレート 40 個入りパッケージ、96 ウェルプレート、電磁ビーズベースのアッセイ時 Bio-Plex Pro 洗浄ステーションで使用 Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead-based assays /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/171-025001b_tn.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/171-025001b_view.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_feature/global/171-025001b_feature.jpg RepEx Bio-Plex用フラットボトムプレート 96well x40プレート<br> 磁気ビーズに対応した洗浄装置用(Bio-Plex Pro Wash StationもしくはHandHeld Magnetic Washer)プレート 09/21/09 12:07 PM 12/31/37 11:59 PM JP ja LSR /ja_JP/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine N 0 false false false /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171025001&CartQuote=QT&quantity= 1490 false true false ¥48,000 false null /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171025001&AddToDefaultWishList=true&quantity= false false true 41122100 true false true false true /prd/ja/JP/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171025001&quantity= 171025001
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Number Description オプション
10033631 Instruction Manual, Bio-Plex Pro™ RBM Apoptosis Assays, Rev A Click to download
10033632 Bio-Plex Pro™ RBM Apoptosis Assays, Quick Guide, Rev B Click to download
6474 Bio-Plex Pro RBM Apoptosis Assays, Product Information Sheet, Rev A Click to download [ Add to Cart (Free) ]
6458 Bio-Plex Success Guide/Assay Sample Prep, Rev B Click to download
6518 Multiplex Analysis of Cell Death Markers Using Bio-Plex Pro RBM Apoptosis Assays, Rev A Click to download

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All rights reserved. This page was last edited on {0} true True GTM-MJ2DN2S jp JP ja LSR life-science-research life-science-research /prd/ja/JP/direct/biorad?ts=1&cmd=OrdersWorkspaceDisplay /prd/ja/JP/direct/biorad?ts=1&cmd=QuotesWorkspaceDisplay /prd/ja/JP/direct/biorad?ts=1&cmd=InvoiceWorkspaceDisplay&_Tab=Invoice false false true false true true 1040988879 LHsYCOu_wQMQz_Ww8AM window.google_tag_params true 272-THL-329 username CartID_ WT_FPC <script type="text/javascript">$.ajax({url: document.location.protocol + '//munchkin.marketo.net/munchkin.js',dataType: 'script',cache: true,success: function() {Munchkin.init('044-CBN-599');}});</script> <script type="text/javascript" src="/evportal/framework/skins/evolution/js/proxyMunchkin.js"></script> 2019