Process Hardware Components

The pressure relief valve protects Bio-Rad process-scale chromatography columns and the Bio-Rad bubble trap from damage during loading of media and column operation. An option for any Bio-Rad process chromatography column, the valve can be attached easily with clamp connections to the top of the column (T-connection) or to the cover of the bubble trap. Read more.

Optimize Column Operation and Handling of Media

The Bio-Rad media slurry tank is a stand-alone accessory. It can be used with Bio-Rad EasyPack columns combined with a transfer pump, and it can be used with Bio-Rad InPlace columns combined with a Bio-Rad media transfer device. The tank is available in 100, 300, 500, or 900 L sizes; each has one access lid, one top inlet with clamp connection, and one lower outlet with clamp connection. The tank bottom is sloped
for optimized drainability.

The tank uses an agitator with a double propeller to ensure that media are mixed properly and a rotating spray ball for cleaning in place. The tank is designed for use at atmospheric pressure. Material certificates, welding certification, surface finish report, pickling and passivation report, and instruction manual are included.

The Bio-Rad media slurry tank fulfills several functions:

• Resuspends slurry even after complete settlement of the media
• Maintains slurry in suspension during transfer of media to the column
• Rinses interior after media transfer to ensure complete removal of the media
• Cleans and chemically sanitizes tank using spray ball
• Receives resin and rinsing buffer from column during unpacking

The Bio-Rad media slurry tank is also suitable for use with other manufacturers' columns.

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Pack Process Chromatography Columns Easily Using Bio-Rad Packing Motors

All Bio-Rad process chromatography columns can benefit from the addition of a Bio-Rad packing motor. A top motor adjusts the height of the adaptor and packs the column via axial compression. Use of the Bio-Rad packing motor eliminates the need to manually activate the central screw. The variable frequency drive of the motor enables highly reproducible axial compression packing.

Motorized axial compression is strongly recommended for columns of diameters between 200 and 1,000 mm; it is compulsory for columns of diameters 1,000 mm and greater.

The motor is controlled by a variable frequency drive installed in an electrical cabinet. The speed of the top piston can be easily adjusted with the potentiometer.

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Take Columns Off-Line With Column Valve Accessory

Isolation two-way valves are attached to the process chromatography column inlet and outlet to isolate the column from the environment during downtime or storage. Isolation two-way valves can also be used for priming the central screw. The valves are attached easily with clamp connections at the top and bottom of the column.

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