Stem Cell Research - Citations
Direct reprogramming of human neural stem cells by OCT4
Nature PMID 19718018
Nature PMID 19718018
Author(s): Jeong Beom Kim, Boris Greber, Marcos J Araúzo-Bravo, Johann Meyer, Kook In Park, Holm Zaehres, Hans R Schöler
Abstract: Induced pluripotent stem (iPS) cells have been generated from mouse and human somatic cells by ectopic expression of four transcription factors (OCT4 ... read more »
Abstract: Induced pluripotent stem (iPS) cells have been generated from mouse and human somatic cells by ectopic expression of four transcription factors (OCT4 ... read more »
Embryonic stem cell-specific microRNAs promote induced pluripotency.
Nat Biotechnol PMID 19363475
Nat Biotechnol PMID 19363475
Author(s): Robert L Judson, Joshua E Babiarz, Monica Venere, Robert Blelloch
Abstract: This report demonstrates that introduction of microRNAs (miRNAs) specific to embryonic stem cells enhances the production of mouse induced pluripotent... read more »
Abstract: This report demonstrates that introduction of microRNAs (miRNAs) specific to embryonic stem cells enhances the production of mouse induced pluripotent... read more »
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
Cell PMID 19269371
Cell PMID 19269371
Author(s): Frank Soldner, Dirk Hockemeyer, Caroline Beard, Qing Gao, George W Bell, Elizabeth G Cook, Gunnar Hargus, Alexandra Blak, Oliver Cooper, Maisam Mitalipova, Ole Isacson, Rudolf Jaenisch
Abstract: Induced pluripotent stem cells (iPSCs) derived from somatic cells of patients represent a powerful tool for biomedical research and may provide a sour... read more »
Abstract: Induced pluripotent stem cells (iPSCs) derived from somatic cells of patients represent a powerful tool for biomedical research and may provide a sour... read more »
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons.
Science PMID 18669821
Science PMID 18669821
Author(s): John T Dimos, Kit T Rodolfa, Kathy K Niakan, Laurin M Weisenthal, Hiroshi Mitsumoto, Wendy Chung, Gist F Croft, Genevieve Saphier, Rudy Leibel, Robin Goland, Hynek Wichterle, Christopher E Henderson, Kevin Eggan
Abstract: The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient... read more »
Abstract: The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient... read more »
Pluripotent stem cell lines.
Genes Dev PMID 18676805
Genes Dev PMID 18676805
Author(s): Junying J Yu, James A JA Thomson
Abstract: The derivation of human embryonic stem cells 10 years ago ignited an explosion of public interest in stem cells, yet this achievement depended on prio... read more »
Abstract: The derivation of human embryonic stem cells 10 years ago ignited an explosion of public interest in stem cells, yet this achievement depended on prio... read more »
Dissecting direct reprogramming through integrative genomic analysis.
Nature PMID 18509334
Nature PMID 18509334
Author(s): Tarjei S TS Mikkelsen, Jacob J Hanna, Xiaolan X Zhang, Manching M Ku, Marius M Wernig, Patrick P Schorderet, Bradley E BE Bernstein, Rudolf R Jaenisch, Eric S ES Lander, Alexander A Meissner
Abstract: Somatic cells can be reprogrammed to a pluripotent state through the ectopic expression of defined transcription factors. Understanding the mechanism ... read more »
Abstract: Somatic cells can be reprogrammed to a pluripotent state through the ectopic expression of defined transcription factors. Understanding the mechanism ... read more »
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
Nat Biotechnol PMID 18568017
Nat Biotechnol PMID 18568017
Author(s): Danwei D Huangfu, René R Maehr, Wenjun W Guo, Astrid A Eijkelenboom, Melinda M Snitow, Alice E AE Chen, Douglas A DA Melton
Abstract: Reprogramming of mouse and human somatic cells can be achieved by ectopic expression of transcription factors, but with low efficiencies. We report th... read more »
Abstract: Reprogramming of mouse and human somatic cells can be achieved by ectopic expression of transcription factors, but with low efficiencies. We report th... read more »
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.
Nat Biotechnol PMID 18059259
Nat Biotechnol PMID 18059259
Author(s): Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe, Kazutoshi Takahashi, Tomoko Ichisaka, Takashi Aoi, Keisuke Okita, Yuji Mochiduki, Nanako Takizawa, Shinya Yamanaka
Abstract: Direct reprogramming of somatic cells provides an opportunity to generate patient- or disease-specific pluripotent stem cells. Such induced pluripoten... read more »
Abstract: Direct reprogramming of somatic cells provides an opportunity to generate patient- or disease-specific pluripotent stem cells. Such induced pluripoten... read more »
Induced pluripotent stem cell lines derived from human somatic cells.
Science PMID 18029452
Science PMID 18029452
Author(s): Junying Yu, Maxim A Vodyanik, Kim Smuga-Otto, Jessica Antosiewicz-Bourget, Jennifer L Frane, Shulan Tian, Jeff Nie, Gudrun A Jonsdottir, Victor Ruotti, Ron Stewart, Igor I Slukvin, James A Thomson
Abstract: Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated stat... read more »
Abstract: Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated stat... read more »
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
Cell PMID 18035408
Cell PMID 18035408
Author(s): Kazutoshi K Takahashi, Koji K Tanabe, Mari M Ohnuki, Megumi M Narita, Tomoko T Ichisaka, Kiichiro K Tomoda, Shinya S Yamanaka
Abstract: Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem cel... read more »
Abstract: Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem cel... read more »
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