Epigenetics and Chromatin Structure - Citations
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DNA demethylases: a new epigenetic frontier in drug discovery.
Drug Discov Today PMID 21601651
Drug Discov Today PMID 21601651
Author(s): Nessa N Carey, C Joana CJ Marques, Wolf W Reik
Abstract: DNA methylation is one of the most extensively studied, and one of the most stable, of all epigenetic modifications. Two drugs that target DNA methylt... read more »
Abstract: DNA methylation is one of the most extensively studied, and one of the most stable, of all epigenetic modifications. Two drugs that target DNA methylt... read more »
The tumorigenicity of human embryonic and induced pluripotent stem cells
Nat Rev Cancer PMID 21390058
Nat Rev Cancer PMID 21390058
Author(s): Uri Ben-David, Nissim Benvenisty
Abstract: The unique abilities of human pluripotent stem cells to self-renew and to differentiate into cells of the three germ layers make them ... read more »
Abstract: The unique abilities of human pluripotent stem cells to self-renew and to differentiate into cells of the three germ layers make them ... read more »
The epigenome as a therapeutic target in prostate cancer.
Nat Rev Urol PMID 21060342
Nat Rev Urol PMID 21060342
Author(s): Antoinette S Perry, R William G Watson, Mark Lawler, Donal Hollywood
Abstract: During cancer development and progression, tumor cells undergo abnormal epigenetic modifications, including DNA methylation, histone deacetylation and... read more »
Abstract: During cancer development and progression, tumor cells undergo abnormal epigenetic modifications, including DNA methylation, histone deacetylation and... read more »
Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers.
Nat Rev Cancer PMID 20574448
Nat Rev Cancer PMID 20574448
Author(s): Ping Chi, C David Allis, Gang Greg Wang
Abstract: Post-translational modification of histones provides an important regulatory platform for processes such as gene transcription and DNA damage repair. ... read more »
Abstract: Post-translational modification of histones provides an important regulatory platform for processes such as gene transcription and DNA damage repair. ... read more »
Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs.
Curr Opin Mol Ther PMID 20373265
Curr Opin Mol Ther PMID 20373265
Author(s): Barbora B Malecová, Kevin V KV Morris
Abstract: Chromatin remodeling guided by non-coding RNA (ncRNA) contributes mechanistically to the establishment of chromatin structure and to the maintenance o... read more »
Abstract: Chromatin remodeling guided by non-coding RNA (ncRNA) contributes mechanistically to the establishment of chromatin structure and to the maintenance o... read more »
Principles and challenges of genomewide DNA methylation analysis.
Nat Rev Genet PMID 20125086
Nat Rev Genet PMID 20125086
Author(s): Peter W Laird
Abstract: Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and ... read more »
Abstract: Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and ... read more »
Imprinting and transgenerational modulation of gene expression; human growth as a model.
Acta Genet Med Gemellol (Roma) PMID 8872020
Acta Genet Med Gemellol (Roma) PMID 8872020
Author(s): M M Pembrey
Abstract: It is proposed that transgenerational modulation of gene expression might be possible, if the metabolic response of the parent to some physiological o... read more »
Abstract: It is proposed that transgenerational modulation of gene expression might be possible, if the metabolic response of the parent to some physiological o... read more »
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