Used with the ProteOn™ XPR36 protein interaction array system, ProteOn sensor chips are prepared with a modified alginate polymer layer bound to the gold surface of the sensor prism. This layer provides the net negative charge and active binding sites for ligand immobilization. The result is user-controlled sensitivity down to the subnanogram level.
The ProteOn GLH sensor chip is designed for general amine coupling and has a highly extended mixed polymer layer with maximum binding capacity. It is suitable for various applications including protein–small molecule and protein-protein interaction.
Each ProteOn sensor chip is enclosed in a bar-coded cartridge for data tracking and archiving. Chips have long-term storage stability and all six ligand channels may be used across different experiments.
The ProteOn XPR36 system includes all of the components required for interaction analysis: instrumentation, ProteOn Manager™ software, sensor chips, buffer and reagent kits, and protocol development kits.