Squamous Cell Carcinoma Antigen 1 (SCCA-1)

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Squamous Cell Carcinoma Antigen 1 (SCCA-1)


SCCA-1 (squamous cell carcinoma antigen 1) is coded by the SERPINB3 gene (serpin peptidase inhibitor, clade B (ovalbumin), member 3) and has a molecular weight of ~44.5 kD, and is a subfraction of the tumor associated antigen TA-4.  SCCA-1 is a useful tumor marker for detecting, staging & for monitoring response to therapy in patients with squamous cell carcinoma of the lung.  It may also act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells and may also function as an inhibitor of UV-induced apoptosis via suppression of the JNK1 activity (c-JUN (NH (2)-terminal Kinase)).

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r-SCCA-1 Ag.

12000860
Source: Human CHO Cell Line. Concentration: ≥ 100 µg/mL. Form: Liquid in Phosphate Buffered Saline pH 7.4 ± 0.1

12000860 /templatedata/internet/product_SKU/data/CDG/Critical-Raw-Materials/Antigens/12000860_1468454907.xml 12000860 07/13/16 04:51 PM N en 07/13/26 05:07 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA CDG 2017-11-14 07:06:24 12000860-r-scca-1-ag 12000860 r-SCCA-1 Ag. r-SCCA-1 Ag. Source: Human CHO Cell Line. Concentration: &ge; 100 µg/mL. Form: Liquid in Phosphate Buffered Saline pH 7.4 &plusmn; 0.1 Source: Human CHO Cell Line. Concentration: &ge; 100 µg/mL. Form: Liquid in Phosphate Buffered Saline pH 7.4 &plusmn; 0.1 /webroot/web/images/cdg/products/critical_raw_materials/sku_thumb/global/crm_27502300_tn.jpg /webroot/web/images/cdg/products/critical_raw_materials/sku_view/global/crm_27502300_view.jpg /webroot/web/images/cdg/products/critical_raw_materials/sku_feature/global/crm_27502300_feature.jpg r-SCCA-1 Ag. preview Ana Davidson r-SCCA-1 Ag. Source: Human CHO Cell Line. Concentration: &ge; 100 µg/mL. Form: Liquid in Phosphate Buffered Saline pH 7.4 &plusmn; 0.1 Squamous Cell Carcinoma Antigen 1 (SCCA-1) 07/13/16 04:51 PM 07/13/26 05:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Critical-Raw-Materials/Antigens N 0 <p><strong>Grade:</strong> Partially Purified<br /> <strong>Concentration:</strong> &ge; 100 &micro;g/mL Abbott Architect SCCA-1 Assay<br /> <strong>Source:</strong> CHO Cell Line<br /> <strong>Form:</strong> Liquid in Phosphate Buffered Saline pH 7.4 &plusmn; 0.1<br /> <strong>Filtration:</strong> 0.2&micro;<br /> <strong>Use:</strong>This partially purified product can be used to make standards or calibrators, and is recommended for use in multianalyte controls.<br /> <strong>Purity Ratio:</strong> TBD<br /> <strong>Storage:</strong> 20&deg;C<br /> <strong>Shelf Life:</strong> TBD<br /> <strong>Viral testing: </strong>N/A</p> /webroot/web/html/cdg/products/critical_raw_materials/sku_view/description/global crm_squamous_rscca1ag_sku_desc.html /webroot/web/html/cdg/products/critical_raw_materials/sku_view/description/global/crm_squamous_rscca1ag_sku_desc.html 1 0 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=12000860&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=12000860&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=12000860&quantity= 12000860
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