Bio-Scale Mini UNOsphere Rapid S cartridges have a double-wall cartridge design* that provides extra durability and allows easy, reliable runs at pressures up to 45 psi with aqueous buffers most commonly used for protein separation. Bio-Scale Mini UNOsphere Rapid S cartridges are convenient, disposable, and ready to use. The cartridges come in 1 and 5 ml formats that can be used for method scouting or simple purifications. The simple luer connections can connect easily to any chromatography system (for column connection guide, refer to bulletin 5326).
Achieve High Productivity Using UNOsphere Rapid S Cation Exchange Media
UNOsphere Rapid S support is a strong cation exchange support for process chromatography. The support has been optimized to deliver speed and throughput in capture and intermediate purification steps. UNOsphere Rapid S support combines high binding capacity, fast mass transfer, excellent flow characteristics, and robust physical properties to make it an exceptional choice for process chromatography.
Stands Up to Sanitization and Cleaning
The performance of UNOsphere Rapid S support is not compromised by exposure to NaOH in commonly used sanitization and clean-in-place protocols.
High Flow at Low Backpressure
The macroporous structure of the UNOsphere matrix affords the use of high flow rates while maintaining very low backpressures. With typical buffers and running conditions, it is possible to achieve linear velocities in excess of 1,000 cm/hr in full-scale columns with backpressures below 2 bar.
Designed for Reproducibility
UNOsphere media are based on a unique polymerization process, which yields macroporous, hydrophilic beads that are ideal for biomolecule separations. Incorporation of the sulfonic acid ligand directly into the matrix during the polymerization process ensures consistent batch-to-batch and run-to-run reproducibility.
* U.S. Patent 7,208,087.