Macro-Prep® Cation Exchange Resin

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Macro-Prep Cation Exchange Resin

Overview

Specifications
Property DEAE High Q High S CM
Type of support Weak anion Strong anion Strong cation Weak cation
Functional ligand –N+(C2H5)2 –N+(CH3)3 –SO3- –COO-
Ionic capacity 175 ±75 µeq/ml 400 ±75 µeq/ml 160 ±40 µeq/ml 210 ±40 µeq/ml
Typcial binding capacity 35 mg BSA/ml 40 mg BSA/ml 70 mg IgG*/ml 35 mg hemoglobin/ml
Counterion Cl- Cl- NA+ NA+
Nominal particle size 50 µm 50 µm 50 µm 50 µm
Nominal pore size 1,000 Å 1,000 Å 1,000 Å 1,000 Å
Recommended maximum linear flow rate 3,000 cm/hr 3,000 cm/hr 3,000 cm/hr 3,000 cm/hr
Chemical stability
    1% SDS, 24 hr Yes Yes Yes Yes
    6 M guanidine-HCl, 24 hr Yes Yes Yes Yes
Volume changes
    pH 4–10 <1% <1% <3% <1%
    0.1–1.0 M NaCl <5% <5% <9% <4%
Autoclavability
(121°C, 80 min)
Yes Yes Yes Yes
pH stability 1–10 1–10 1–12 1–12
Antimicrobial agent 20% ethanol 20% ethanol 20% ethanol 20% ethanol
Regeneration 1 M NaCl 1 M NaCl 1 M NaCl 1 M NaCl

* Human IgG.

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Macro-Prep High S strong cation exchange support meets the demands of analytical, semipreparative, and process-scale applications. This rigid, macroporous hydrophilic support provides exceptional capacity, resolution, and throughput in a chemically and mechanically stable form.

All Macro-Prep resin operate well at low and medium pressures and exhibit minimal volume changes in response to variations in pH or ionic strength. These resins provide consistent and reproducible results.

Key Features

  • High capacity for biomolecules
  • High resolution of complex biological mixtures
  • Rigid polymer matrix that allows high flow rates at moderate pressures
  • Hydrophilic matrix that reduces nonspecific binding
  • Macroporous beads that enhance access to ionic sites
  • Chemical, mechanical, and thermal stability

 

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Macro-Prep High S Support

1580030
25 ml, strong cation exchange chromatography media, 50 μm particle size

0 1580030 /templatedata/internet/product_SKU/data/LSR/Chromatography/Chromatography-Media/158-0030_0921120702313.xml 1580030 09/21/09 12:07 PM N en 09/21/19 12:07 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA LSR 2017-11-14 07:08:03 1580030-macro-prep-high-s-support 1580030 Macro-Prep High S Support Macro-Prep High S Support 25 ml, strong cation exchange chromatography media, 50 μm particle size 25 ml, strong cation exchange chromatography media, 50 μm particle size 25 ml, strong cation exchange chromatography media, 50 μm particle size /webroot/web/images/ps/products/ion_exchange_media/sku_thumb/global/158-0030_tn.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_view/global/158-0030_view.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_feature/global/158-0030_feature.jpg RepEx 158-0030 25 ml, strong cation exchange chromatography media, 50 μm particle size 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Chromatography/Chromatography-Media N 0 1580030, macro-prep, high, s, support, strong, cation, ion, exchange, iex, chromatography, media, medium, resin, protein, separation, purification, 50um, 50, particle, size false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1580030&CartQuote=QT&quantity= false true false $51.00 false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1580030&AddToDefaultWishList=true&quantity= true false true true false true true true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1580030&quantity= 1580030
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Macro-Prep High S Support

1560030
100 ml, strong cation exchange chromatography media, 50 μm particle size

1 1560030 /templatedata/internet/product_SKU/data/LSR/Chromatography/Chromatography-Media/156-0030_0921120702276.xml 1560030 09/21/09 12:07 PM N en 09/21/19 12:07 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA LSR 2017-11-14 07:08:02 1560030-macro-prep-high-s-support 1560030 Macro-Prep High S Support Macro-Prep High S Support 100 ml, strong cation exchange chromatography media, 50 μm particle size 100 ml, strong cation exchange chromatography media, 50 μm particle size 100 ml, strong cation exchange chromatography media, 50 μm particle size /webroot/web/images/ps/products/ion_exchange_media/sku_thumb/global/156-0030_tn.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_view/global/156-0030_view.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_feature/global/156-0030_feature.jpg RepEx Macro-Prep High S Support #156-0031 100 ml, strong cation exchange chromatography media, 50 μm particle size 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Chromatography/Chromatography-Media N 0 1560030, macro-prep, high, s, support, strong, cation, exchange, iex, ion, chromatography, media, medium, resin, protein, separation, purification, 50um, 50, particle, size Macro-Prep High S Support #156-0031 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560030&CartQuote=QT&quantity= false true false $168.00 false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560030&AddToDefaultWishList=true&quantity= true false true true false true true true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560030&quantity= 1560030
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Macro-Prep High S Support

1560031
500 ml, strong cation exchange chromatography media, 50 μm particle size

2 1560031 /templatedata/internet/product_SKU/data/LSR/Chromatography/Chromatography-Media/156-0031_0921120702234.xml 1560031 09/21/09 12:07 PM N en 09/21/19 12:07 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA LSR 2017-11-14 07:08:02 1560031-macro-prep-high-s-support 1560031 Macro-Prep High S Support Macro-Prep High S Support 500 ml, strong cation exchange chromatography media, 50 μm particle size 500 ml, strong cation exchange chromatography media, 50 μm particle size 500 ml, strong cation exchange chromatography media, 50 μm particle size /webroot/web/images/ps/products/ion_exchange_media/sku_thumb/global/156-0031_tn.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_view/global/156-0031_view.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_feature/global/156-0031_feature.jpg RepEx Macro-Prep High S Support #156-0032 500 ml, strong cation exchange chromatography media, 50 μm particle size 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Chromatography/Chromatography-Media N 0 1560031, macro-prep, high, s, support, strong, cation, exchange, iex, ion, chromatography, media, medium, resin, protein, separation, purification, 50um, 50, particle, size Macro-Prep High S Support #156-0032 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560031&CartQuote=QT&quantity= false true false $620.00 false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560031&AddToDefaultWishList=true&quantity= true false true true false true true true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560031&quantity= 1560031
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Macro-Prep High S Support

156-0032
5 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

3 1560032 /templatedata/internet/product_SKU/data/LSR/Chromatography/Chromatography-Media/156-0032_0921120702297.xml 1560032 09/21/09 12:07 PM N en 09/21/19 12:07 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA LSR 2017-11-14 07:08:02 1560032-macro-prep-high-s-support 1560032 Macro-Prep High S Support Macro-Prep High S Support 5 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size 5 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size 5 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size /webroot/web/images/ps/products/ion_exchange_media/sku_thumb/global/156-0032_tn.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_view/global/156-0032_view.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_feature/global/156-0032_feature.jpg RepEx Macro-Prep High S Support #156-0033 5 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Chromatography/Chromatography-Media N 0 1560032, macro-prep, high, s, support, strong, cation, exchange, iex, ion, chromatography, media, medium, resin, protein, separation, purification, analytical, semi-preparative, process, scale, 50um, 50, particle, size Macro-Prep High S Support #156-0033 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560032&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560032&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560032&quantity= 156-0032
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Macro-Prep High S Support

156-0033
10 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

4 1560033 /templatedata/internet/product_SKU/data/LSR/Chromatography/Chromatography-Media/156-0033_0921120702255.xml 1560033 09/21/09 12:07 PM N en 09/21/19 12:07 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA LSR 2017-11-14 07:08:02 1560033-macro-prep-high-s-support 1560033 Macro-Prep High S Support Macro-Prep High S Support 10 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size 10 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size 10 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size /webroot/web/images/ps/products/ion_exchange_media/sku_thumb/global/156-0033_tn.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_view/global/156-0033_view.jpg /webroot/web/images/ps/products/ion_exchange_media/sku_feature/global/156-0033_feature.jpg RepEx 156-0033 10 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Chromatography/Chromatography-Media N 0 1560033, macro-prep, high, s, support, strong, cation, exchange, iex, ion, chromatography, media, medium, resin, protein, separation, purification, analytical, semi-preparative, process, scale, 50um, 50, particle, size false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560033&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560033&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=1560033&quantity= 156-0033
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Number Description Options
LIT271 Instruction Manual, Macro-Prep Ion Exchange Supports, Rev D Click to download
2292 Macro-Prep Ion Exchange Supports Product Information Sheet, Rev A Click to download
5643 Macro-Prep® High S Support Product Information Sheet, Rev A Click to download
6983 Native and Recombinant Protein Purification Resins/Media Selection Card Click to download
6868 Macro-Prep® Chromatography Resins Publications List, Ver A Click to download
2026 Evaluation of Different Approaches for the Chromatographic Purification of Monoclonal Antibodies Click to download
1913 Developing and Scaling Up a Purification Procedure With Two New Ion Exchange Supports (Poster), Rev B Click to download
1985 Clearance of Murine Leukemia Virus From a Chimeric Monoclonal Antibody Using Ion Exchange Chromatography, Rev B. Click to download

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