Bio-Rad's KnowItAll Stereochemistry Toolkit (TK) provides a fast, efficient, and highly reliable platform for the interpretation of implicit stereochemical information in traditionally-drawn structures that allows them to be used for indexing, searching, and other forms of processing. In addition, the Bio-Rad Stereochemistry TK generates accurate Cahn-Ingold-Prelog (CIP) stereodescriptors defined in the IUPAC Nomenclature of Organic Chemistry (Blue Book) for all descriptor classes (R/S, E/Z, M/P) of organic molecules.
- Interprets implicit stereochemical information in the original structure without conversion or loss of information. Includes: Wedged, hashed, and hashed wedged bonds, chair/boat projections in any orientation in space, Haworth projections in any orientation in space, Fischer projections in any orientation in space, pseudo-3D projections (2.5D projections)
- Calculates parity information for every found stereocenter to allow structures to be matched correctly regardless of their drawing style, which is critical for database building, searching, indexing, web publishing, etc.
- Gives feedback on stereocenters that could not be interpreted because of ambiguities or errors in the drawing style, which can be used to clean up structures