Ferritin

Print
Ferritin

Ferritins (MW: ~ 450 kD) are polymeric proteins composed of 2 subunits a heavy chain and a light chain polypeptide, that reversibly bind and store iron in liver, spleen and bone marrow. The ferritin molecule consists of 24 self-assembling polypeptide subunits composed of the heavy and light chains. Ferritin light chain is the main intracellular iron storage protein. The proportion of heavy and light chain composing the ferritin molecule varies from tissue to tissue. This variation accounts for the differences in the rate of iron uptake and release in different tissues or organs. Recombinant Human Ferritin Light Chain is produced in E.coli as a single non-glycosylated polypeptide having a molecular weight of 19 kDa. Clinically, the monitoring of serum ferritin levels aides in the diagnosis and management of iron metabolic disorders. Serum levels increase in hepatic diseases, various malignancies, inflammation and late stage hemochromatosis. Ferritin levels are also indicative of the erosion of iron stores during pregnancy. Genetic defects in the light chain ferritin gene are linked with several neurodegenerative disorders.

x

Account price failed to display. Please try reloading the page. Reload Page

If you are placing an order, you may proceed with your order; the account price will be applied if it is lower than the
list price. If the problem persists, please call customer service at   or send an
email to 

r-Ferritin Ag., Lt Chain, HP
r-Ferritin Ag., Lt Chain, HP

12000196
Source: E. coli. Concentration: 3.25 - 10 mg/mL. Form: Liquid in Phosphate Buffered Saline, pH 7.4 ± 0.2

List Price:
 
Inquire
Loading
Your Price:
 

Communication error

Reload Page

Quantity:   Add to Quote
Add to Hot List