Ferritin

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Ferritin


Ferritins (MW: ~ 450 kD) are polymeric proteins composed of 2 subunits a heavy chain and a light chain polypeptide, that reversibly bind and store iron in liver, spleen and bone marrow. The ferritin molecule consists of 24 self-assembling polypeptide subunits composed of the heavy and light chains. Ferritin light chain is the main intracellular iron storage protein. The proportion of heavy and light chain composing the ferritin molecule varies from tissue to tissue. This variation accounts for the differences in the rate of iron uptake and release in different tissues or organs. Recombinant Human Ferritin Light Chain is produced in E.coli as a single non-glycosylated polypeptide having a molecular weight of 19 kDa. Clinically, the monitoring of serum ferritin levels aides in the diagnosis and management of iron metabolic disorders. Serum levels increase in hepatic diseases, various malignancies, inflammation and late stage hemochromatosis. Ferritin levels are also indicative of the erosion of iron stores during pregnancy. Genetic defects in the light chain ferritin gene are linked with several neurodegenerative disorders.

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r-Ferritin Ag., Lt Chain, HP

12000196
Source: E. coli. Concentration: 3.25 - 10 mg/mL. Form: Liquid in Phosphate Buffered Saline, pH 7.4 ± 0.2

12000196 /templatedata/internet/product_SKU/data/CDG/Critical-Raw-Materials/Antigens/12000196_1384994571.xml 12000196 11/20/13 04:23 PM N en 11/20/23 04:32 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA CDG 2017-11-14 07:06:24 12000196-r-ferritin-ag-lt-chain-hp 12000196 r-Ferritin Ag., Lt Chain, HP r-Ferritin Ag., Lt Chain, HP Source: E. coli. Concentration: 3.25 - 10 mg/mL. Form: Liquid in Phosphate Buffered Saline, pH 7.4 &plusmn; 0.2 Source: E. coli. Concentration: 3.25 - 10 mg/mL. Form: Liquid in Phosphate Buffered Saline, pH 7.4 &plusmn; 0.2 /webroot/web/images/cdg/products/critical_raw_materials/sku_thumb/global/crm_42602300_tn.jpg /webroot/web/images/cdg/products/critical_raw_materials/sku_view/global/crm_42602300_view.jpg /webroot/web/images/cdg/products/critical_raw_materials/sku_feature/global/crm_42602300_feature.jpg r-Ferritin Ag., Lt Chain, HP preview Ana Davidson r-Ferritin Ag., Lt Chain, HP Source: E. coli. Concentration: 3.25 - 10 mg/mL. Form: Liquid in Phosphate Buffered Saline, pH 7.4 &plusmn; 0.2 r-Ferritin Ag., Lt Chain, HP, Source: E. coli. Concentration: 3.25 - 10 mg/mL. Form: Liquid in Phosphate Buffered Saline, pH 7.4 &plusmn; 0.2 11/20/13 04:23 PM 11/20/23 04:32 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Critical-Raw-Materials/Antigens N 0 <p><strong>Grade:</strong> Highly Purified<br /><strong>Concentration:</strong> 3.25 - 10 mg/ml Centaur Ferritin Assay <br /><strong>Source:</strong> E. coli<br /><strong>Form:</strong> Liquid in Phosphate Buffered Saline, pH 7.4 &plusmn; 0.2<br /><strong>Filtration:</strong> 0.2&micro;<br /><strong>Use:</strong> This highly purified product is recommended for use as a single analyte standard or control and in multianalyte controls<br /><strong>Purity Ratio:</strong> &gt; 95% by PAGE - Multiple Characteristics Bands Visible as Confirmed by Blot<br /><strong>Storage:</strong> -20&deg;C<br /><strong>Shelf Life:</strong> 2 Years (stored at recommended long term temperature)<br /><strong>Viral Testing:</strong> N/A</p> /webroot/web/html/cdg/products/critical_raw_materials/sku_view/description/global crm_r_ferritin_ag_lt_chain_hp_sku_desc.html /webroot/web/html/cdg/products/critical_raw_materials/sku_view/description/global/crm_r_ferritin_ag_lt_chain_hp_sku_desc.html 1 0 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=12000196&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=12000196&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=12000196&quantity= 12000196
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