BioPlex® 2200 Vasculitis

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Overview

BioPlex® 2200 Vasculitis

Vasculitis Assay Procedure

1. Patient sample (5 µL) automatically added to
    reaction vessel

2. Sample diluent & beads added
    and incubated at 37°C

3. Wash step

4. Conjugate added and incubated at 37°C

5. Wash step

6. Bead resuspended in wash buffer

7. Flow-based, dual laser detection

BioPlex® 2200 Vasculitis

Reagents, Calibrators and Controls

Vasculitis Reagent Pack

Contains all the necessary reagents (sample diluent, beads, and conjugate) to process 100 samples and up to 3 results per sample.

 

Vasculitis Calibrator Set

Calibrators are ready-to-use and multiplexed. A point-to-point curve fit using four calibrators is used to calculate semi-quantitative results.

Vasculitis Control Set

Quality controls are ready-to-use and multiplexed. The set includes a negative control as well as a multianalyte positive control containing antibodies to analytes within the Reagent Pack.

BioPlex® 2200 Vasculitis is the first and only fully automated, random access multiplexed solution that detects the most clinically relevant antibodies associated with systemic small vessel vasculitis: anti-MPO, anti-PR3, and anti-GBM.

This multiplex flow immunoassay is intended for the semi-quantitative detection of IgG autoantibodies to myeloperoxidase (MPO), proteinase 3 (PR3) and glomerular basement membrane (GBM) in human serum. In conjunction with clinical findings, the test system is used as an aid in the diagnosis of anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides: microscopic polyangiitis (MPA), necrotizing glomerulonephritis, Churg-Strauss syndrome, Wegener’s granulomatosis, and the autoimmune renal disorder Goodpasture’s syndrome.

BioPlex 2200 Vasculitis Reagent Pack
BioPlex 2200 Vasculitis Reagent Pack

665-1850
Reagents for 100 tests for anti-MPO, anti-PR3, and anti-GBM; aids in diagnosis of autoimmune vasculitides and Goodpasture’s syndrome

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BioPlex 2200 Vasculitis Calibrator Set
BioPlex 2200 Vasculitis Calibrator Set

663-1800
Multiplexed standard analytes for calibration of results of vasculitis screening on BioPlex 2200 System

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BioPlex 2200 Vasculitis Calibrator CD
BioPlex 2200 Vasculitis Calibrator CD

663-1820
CD with software to verify calibration of vasculitis screening on BioPlex 2200 System

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BioPlex 2200 Vasculitis Control Set
BioPlex 2200 Vasculitis Control Set

663-1830
Set of multiplexed negative and multianalyte (anti-MPO, anti-PR3, anti-GBM) positive controls for vasculitis testing on BioPlex 2200 System

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BioPlex 2200 Vasculitis Control CD
BioPlex 2200 Vasculitis Control CD

663-1840
CD with software to check performance of controls in vasculitis screening on BioPlex 2200 System

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