BioPlex® 2200 EBV IgM

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EBV IgM

Overview

BioPlex® 2200 EBV IgG and IgM

EBV Infection Diagnosis

Infectious Mononucleosis (IM) diagnosis is typically based on the detection of heterophile antibodies and antibodies against specific Epstein-Barr virus antigens:

  • Viral Capsid Antigen: EBV VCA IgG and EBV VCA IgM
  • Nuclear Antigen: EBV NA-1 IgG
  • Early Antigen: EBV EA-D IgG

Combining heterophile IgM and VCA IgM detection enhances the detection of acute IM. Determining the complete patient EBV serological profile is essential to define the stage of the infection.



Adapted from: J.M. Seigneurin, Apport du laboratoire dans l’infection à virus Epstein-Barr. Laboratory diagnosis of Epstein-Barr virus infections. Immuno-analyse & Biologie Spécialisée 1 (2002) 33–39.

BioPlex® 2200 EBV IgM

EBV IgM Assay Procedure

1. Patient sample (5 µL) automatically added to
    reaction vessel

2. Sample diluent & beads added
    and incubated at 37°C

3. Wash step

4. Conjugate added and incubated at 37°C

5. Wash step

6. Bead resuspended in wash buffer

7. Flow-based, dual laser detection

BioPlex® 2200 EBV IgM

Reagents, Calibrators, and Controls

EBV IgM Reagent Packs

Each contains all the necessary reagents (sample diluent, beads, and conjugate) to process 100 samples per pack and up to 2 (IgM) results per sample.

 

 

   

EBV IgM Calibrator Sets

The EBV IgM kit calibrators are multiplexed and ready-to-use.

 

 

   

EBV IgM Control Sets

The EBV IgM kit controls are multiplexed and ready-to-use.

 

 

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The BioPlex® 2200 EBV IgM kit simultaneously detects the two antibodies of highest clinical significance, including the heterophile antibody, in a multiplex format. The BioPlex heterogeneous assay format (a minimum of 150 readings per analyte) enhances precision and the system can process up to 190 results per hour (EBV IgG and EBV IgM kits combined). All reagents, calibrators, and controls are ready to use and all steps are fully automated, significantly reducing hands-on time and labor costs. Full automation from primary tube to final result minimizes the subjectivity linked to non-EIA methods and improves reproducibility. For every sample, the system also processes three internal quality controls, ensuring the integrity of results.

The system’s powerful eFlex™ software provides maximum control and flexibility. Add on new test orders from previously run samples, create custom EBV panels, and interface bidirectionally with the laboratory information system (LIS). BioPlex® 2200 EBV IgG and IgM kits provide complete information for improved diagnosis, management, and follow-up care of EBV-infected patients.

BioPlex® 2200 EBV IgM reports results for the following antibodies:

  • EBV VCA IgM
  • Heterophile IgM

 

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BioPlex® 2200 EBV IgM Reagent Pack

665-1350
Reagents for 100 tests for clinically relevant IgM antibodies to Epstein-Barr virus on BioPlex® 2200 System; aids in diagnosis of infectious mononucleosis

6651350 /templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/665-1350_0921120832490.xml 6651350 /default/main/bio-rad/WORKAREA/default 09/21/09 12:08 PM en_US jfd8xjpw 2017-11-14 07:06:22 true true internet/product_SKU jfd8xjpw templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/665-1350_0921120832490.xml CDG 2018-04-23 22:54:22 /default/main/bio-rad/STAGING N /default/main/bio-rad en 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2018-04-23 22:54:22 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/665-1350_0921120832490.xml templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/665-1350_0921120832490.xml 6651350-bioplex-2200-ebv-igm-reagent-pack 6651350 BioPlex 2200 EBV IgM Reagent Pack BioPlex<sup>&reg;</sup> 2200 EBV IgM Reagent Pack Reagents for 100 tests for clinically relevant IgM antibodies to Epstein-Barr virus on BioPlex<sup>&reg;</sup> 2200 System; aids in diagnosis of infectious mononucleosis Reagents for 100 tests for clinically relevant IgM antibodies to Epstein-Barr virus on BioPlex 2200 System; aids in diagnosis of infectious mononucleosis Reagents for 100 tests for clinically relevant IgM antibodies to Epstein-Barr virus on BioPlex<sup>&reg;</sup> 2200 System; aids in diagnosis of infectious mononucleosis /webroot/web/images/cdg/products/bioplex_2200/sku_thumb/global/bpx_665_1350_tn.jpg /webroot/web/images/cdg/products/bioplex_2200/sku_view/global/bpx_665_1350_view.jpg /webroot/web/images/cdg/products/bioplex_2200/sku_feature/global/bpx_665_1350_feature.jpg BioPlex<sup>&reg;</sup> 2200 EBV IgM Reagent Pack RepEx BioPlex 2200 EBV IgM Reagent Pack Reagents for 100 tests for clinically relevant IgM antibodies to Epstein-Barr virus on BioPlex 2200 System; aids in diagnosis of infectious mononucleosis ebv igm, vca igm, heterophile, reagents, mutiplexed, ready to use, reportable results, beads, conjugate, sample diluent, internal quality beads, serum verification bead, internal standard bead, reagent blank bead, automatically process 09/21/09 12:08 PM 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas N 0 <p>BioPlex 2200 EBV IgM Reagent Pack contains all the reagents necessary to perform multiplexed EBV IgM assays. Enough ready to use reagents to automatically process 100 patient samples or 200 reportable results. Delivers up to 2 individual reportable results per patient sample. Packs include individual bottles containing beads, conjugate, and sample diluent. Stored at 2&ndash;8&deg; C. Contains 3 Internal Quality beads (IQ beads): the Serum Verification Bead, Internal Standard Bead, and the Reagent Blank Bead.</p> /webroot/web/html/cdg/products/SKUs/autopopulated/ 665-1350_0921120832490_en.html /webroot/web/html/cdg/products/SKUs/autopopulated//665-1350_0921120832490_en.html false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6651350&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6651350&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6651350&quantity= 665-1350
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BioPlex® 2200 EBV IgM Calibrator Set

663-1300
Multiplexed standard analytes for calibration of results of Epstein-Barr virus screening based on IgM antibodies on BioPlex® 2200 System

6631300 /templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1300_0921120832454.xml 6631300 /default/main/bio-rad/WORKAREA/default 09/21/09 12:08 PM en_US jfd8xjrn 2017-11-14 07:06:21 true true internet/product_SKU jfd8xjrn templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1300_0921120832454.xml CDG 2018-04-23 22:54:24 /default/main/bio-rad/STAGING N /default/main/bio-rad en 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2018-04-23 22:54:24 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1300_0921120832454.xml templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1300_0921120832454.xml 6631300-bioplex-2200-ebv-igm-calibrator-set 6631300 BioPlex 2200 EBV IgM Calibrator Set BioPlex<sup>&reg;</sup> 2200 EBV IgM Calibrator Set Multiplexed standard analytes for calibration of results of Epstein-Barr virus screening based on IgM antibodies on BioPlex<sup>&reg;</sup> 2200 System Multiplexed standard analytes for calibration of results of Epstein-Barr virus screening based on IgM antibodies on BioPlex 2200 System Multiplexed standard analytes for calibration of results of Epstein-Barr virus screening based on IgM antibodies on BioPlex<sup>&reg;</sup> 2200 System /webroot/web/images/cdg/products/bioplex_2200/sku_thumb/global/bpx_663_1300_tn.jpg /webroot/web/images/cdg/products/bioplex_2200/sku_view/global/bpx_663_1300_view.jpg /webroot/web/images/cdg/products/bioplex_2200/sku_feature/global/bpx_663_1300_feature.jpg BioPlex<sup>&reg;</sup> 2200 EBV IgM Calibrator Set RepEx BioPlex 2200 EBV IgM Calibrator Set Multiplexed standard analytes for calibration of results of Epstein-Barr virus screening based on IgM antibodies on BioPlex 2200 System ebv igm , heterophile, bioplex 2200, calibrator, calibration, ready-to-use, vials, multi-constituent, automated 09/21/09 12:08 PM 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas N 0 <p>The BioPlex 2200 EBV IgM Calibrator Set is intended for the calibration of the Bioplex 2200 EBV IgM Reagent Pack. EBV IgM calibrator set contains 2 ready-to -use multi-constituent reagents vials (VCA &amp; Heterophile). Open vial stability up to 2 months, tightly capped.</p> /webroot/web/html/cdg/products/SKUs/autopopulated/ 663-1300_0921120832454_en.html /webroot/web/html/cdg/products/SKUs/autopopulated//663-1300_0921120832454_en.html false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6631300&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6631300&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6631300&quantity= 663-1300
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BioPlex® 2200 EBV IgM Control Set

663-1330
Set of multiplexed negative and multianalyte positive controls for Epstein-Barr virus screening based on IgM antibodies on BioPlex® 2200 System

6631330 /templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1330_0921120832472.xml 6631330 /default/main/bio-rad/WORKAREA/default 09/21/09 12:08 PM en_US jfd8xjpz 2017-11-14 07:06:21 true true internet/product_SKU jfd8xjpz templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1330_0921120832472.xml CDG 2018-04-23 22:54:22 /default/main/bio-rad/STAGING N /default/main/bio-rad en 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2018-04-23 22:54:22 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1330_0921120832472.xml templatedata/internet/product_SKU/data/CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas/663-1330_0921120832472.xml 6631330-bioplex-2200-ebv-igm-control-set 6631330 BioPlex 2200 EBV IgM Control Set BioPlex<sup>&reg;</sup> 2200 EBV IgM Control Set Set of multiplexed negative and multianalyte positive controls for Epstein-Barr virus screening based on IgM antibodies on BioPlex<sup>&reg;</sup> 2200 System Set of multiplexed negative and multianalyte positive controls for Epstein-Barr virus screening based on IgM antibodies on BioPlex 2200 System Set of multiplexed negative and multianalyte positive controls for Epstein-Barr virus screening based on IgM antibodies on BioPlex<sup>&reg;</sup> 2200 System /webroot/web/images/cdg/products/bioplex_2200/sku_thumb/global/bpx_663_1330_tn.jpg /webroot/web/images/cdg/products/bioplex_2200/sku_view/global/bpx_663_1330_view.jpg /webroot/web/images/cdg/products/bioplex_2200/sku_feature/global/bpx_663_1330_feature.jpg BioPlex<sup>&reg;</sup> 2200 EBV IgM Control Set RepEx BioPlex 2200 EBV IgM Control Set Set of multiplexed negative and multianalyte positive controls for Epstein-Barr virus screening based on IgM antibodies on BioPlex 2200 System ebv igm, heterophile, bioplex 2200, control set, ready-to-use, vials, multi-constituent, automated, positive, negative, routine testing 09/21/09 12:08 PM 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/BioPlex-2200-Multiplex-Testing/BioPlex-2200-Infectious-Diseas N 0 <p>The BioPlex 2200 EBV IgM Control Set is intended for use as an assayed quality control to monitor the overall performance of the BioPlex 2200 Instrument and BioPlex 2200 EBV IgM Reagent Pack in the clinical laboratory. Includes 2 vials each of positive and negative multi-constituent controls. Contains enough ready to use reagent to allow up to 4 months of routine automated multiplexed QC runs. Open vial stability up to 2 months, tightly capped.</p> /webroot/web/html/cdg/products/SKUs/autopopulated/ 663-1330_0921120832472_en.html /webroot/web/html/cdg/products/SKUs/autopopulated//663-1330_0921120832472_en.html false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6631330&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6631330&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=6631330&quantity= 663-1330
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Number Description Options
T-110 BioPlex EBV Brochure Click to download [ Add to Cart (Free) ]
T-136 BioPlex 2200 Panel Menu Click to download [ Add to Cart (Free) ]
T-158 BioPlex 2200 EBV IgG and IgM Brochure Click to download [ Add to Cart (Free) ]
T-167 BioPlex 2200 Infectious Disease Panels Brochure Click to download [ Add to Cart (Free) ]

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