Bio-Scale Mini CFT Prepacked Cartridges are 5 ml cartridges filled with CFT Ceramic Fluoroapatite Resin. CFT Ceramic Fluoroapatite (Ca10(PO4)6F2) is a rigid, spherical macroporous support used in the purification of biologically active compounds. CFT Ceramic Fluoroapatite Resin is a composite of fluoroapatite and hydroxyapatite prepared by chemically converting hydroxyapatite nanocrystals to fluoroapatite with a fluorine reagent. CFT Resin can be used under stringent chromatography conditions to separate acidic proteins requiring buffered conditions as low as pH 5.6. The cartridges can be used for method scouting or simple purifications.
CFT Resin has a high binding capacity and may be used reproducibly over an extended number of chromatography runs. Its increased tensile strength, chemical durability, and density provide excellent throughput and consistent performance for all separations, including biopharmaceutical process-scale manufacturing.
Features and Benefits of CFT Ceramic Fluoroapatite Resin
- High binding capacity
- Sintering at 700°C (Type II) for heavy-duty, durable supports
- Rigid particles for fast cleaning and equilibration
- Inorganic calcium phosphate for distinct selectivities
Bio-Scale Mini Cartridges have a double-wall cartridge design* that provides extra durability and allows easy, reliable runs at pressures up to 45 psi with the aqueous buffers most commonly used for protein separation. Convenient, disposable, and ready to use, these cartridges are designed for use with BioLogic™ Chromatography Systems, a peristaltic pump, or any chromatography system; luer fittings make connection to any system easy. For simple step elution, the cartridges can be used with a standard syringe.
Bio-Scale™ Mini Cartridges, Product Information Sheet (Bulletin 5584)
Chromatography Column Connection Guide (Bulletin 5326)
Bio-Scale Affi-Prep Protein A Resin Cartridges can also be run on the Profinia™ Protein Purification System.
Low-Pressure Chromatography Fittings are available for connection to HPLC- and FPLC-type systems.
* U.S. Patent 7,208,087.