Bio-Rad Customized Process Skids

Print
Bio-Rad Customized Process Skids

Overview

Specifications
Pressure rating   Up to 6 bar
Temperature range   Ambient: 4–30°C
Process fluids: 4–60°C
Inline dilution capabilities   1:2 to 1:10
Gradient capabilities   10–90%
Material Process tube
Frame
Bubble trap
Gaskets
Stainless steel 316L ASME
Stainless steel 304L
Glass or acrylic
EPDM or GYLON
Bio-Rad Process Chromatography Skid 00 Video


Bio-Rad's process chromatography skid 00 is the industry's first compact skid designed for small-scale GMP biopharmaceutical manufacturing. The skid can be interchanged with multiple columns ranging in diameter from 70 to 300 mm with flow rates from 5 to 120 L/hr. To learn more click the video.

Bio-Rad Process Chromatography Skid 01–05 Specifications
Process
Skid
Category
Flow Rate, L/hr Process Pipe
(ASME BPE)
Maximum Dimensions
(L x W x H), mm
Surface Finish, µm Bubble Trap
Volume, L
Rotary
Diaphragm Pump
Multihead
Diaphragm Pump
00* 5–120 N/A N/A 1,060 x 750 x 610 Ra ≤0.4 0.2
01 5–250 15–165 3/8" 1,500 x 1,000 x 1,700 Ra ≤0.4 0.4
02 25–600 54–540 1/2" 1,500 x 1,000 x 1,700 Ra ≤0.4 1.0
03 40–1,200 105–1,050 3/4" 1,500 x 1,000 x 1,700 Ra ≤0.4 2.7
04 300–3,150 315–3,150 1" Upon request Ra ≤0.4 4.6
05 300–4,500 450–5,400** 1.5" Upon request Ra ≤0.4 4.6

* For more information, request or download bulletin 5997.
** With lobe pump.

Process Skid Categories
Process
Skid
Category
Flow Range (l/h) Process Pipe
(ASME BPE)
Maximum Dimensions
(L x W x H), mm
Surface Finish (µm) Bubble Trap
Volume (l)
Rotary
Diaphragm Pump
Multihead
Diaphragm Pump
0 1–150 3.6–41 1/4" 1,500 x 1,000 x 1,700 Ra≤0.8 0.4
1 5–250 15–165 3/8" 1,500 x 1,000 x 1,700 Ra≤0.4 0.4
2 25–600 54–540 1/2" 1,500 x 1,000 x 1,700 Ra≤0.4 1
3 40–1,200 105–1,050 3/4" 1,500 x 1,000 x 1,700 Ra≤0.4 2.7
4 300–3,150 315–3,150 1" 2,500 x 1,500 x 2,200 Ra≤0.4 4.6
5 450–5,400 450–5,400* 1.5" 2,700 x 1,650 x 2,200 Ra≤0.4 4.6

* With Lobe pump.

Step and Linear Gradient

Step and linear gradient on process chromatography skid size 3 at 1,000 L/H.

Process Skid Software

System overview screen: Intuitive user interface allows for simple data input and user-friendly programming of process sequences.

Process Skid Performance

Compatibility of process skid category and column diameter; isocratic system (flow rate, l/h).


Compatibility of process skid category and column diameter; gradient system (flow rate, l/h).

To read more click here

Bio-Rad Process Chromatography Skid Schematic

Many options exist for customization of the Bio-Rad process chromatography skid.

Scroll upScroll down


Bio-Rad Process Chromatography Skid 01–05

The Bio-Rad process chromatography skid 01–05 allows different options to be integrated into a core platform. Isocratic and gradient systems are optimized for column diameter and process requirements. Other system components, such as pump size and bubble trap volume, are also designed to order.

You may specify combinations of sensors, including flow, pH, conductivity, temperature, pressure, and air sensors. Other options include the orientation and number of valves and ports, an enhanced pressure rating, and clean-in-place and steam-in-place designs.

Options that can be integrated on a process skid include:

  • Multihead dosing pumps
  • Gradient function (controlled by flow rate or flow rate and conductivity)
  • Additional inlet and outlet valves
  • Pressure sensor (before filter or after column)
  • Additional filter
  • Air sensor (after bubble trap or before pump)
  • Conductivity monitor (before column)
  • Temperature sensor (before column)
  • pH monitor (before column)
  • Sampling valve (after column)
  • HETP software
  • Position detector for valves
  • Sterilization-in-place

The computer-driven operation system is passcode protected to record all events and actions in accordance with GMP compliance guidelines. The system controller runs in the Windows operating system. Its simple, user-friendly interface enables touch-screen input of data and programming commands. The software meets U.S. FDA 21 CFR Part 11 requirements.

For more information, please contact your Bio-Rad process sales representative or technical support.

x

Account price failed to display. Please try reloading the page.Reload Page

If you are placing an order, you may proceed with your order; the account price will be applied if it is lower than the
list price. If the problem persists, please call customer service at or send an
email to

(Discontinued)Bio-Rad InPlace Column

7390363
Stainless steel column, 800 mm diameter, 300 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390003
Glass column, 100 mm diameter, 600 mm tube height, for process chromatography.

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390004
Stainless steel column, 100 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390005
Acrylic column, 100 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390006
Glass column, 100 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390007
Stainless steel column, 100 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390008
Stainless steel column, 100 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390056
Stainless steel column, 200 mm diameter, 300 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390057
Stainless steel column, 200 mm diameter, 300 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390058
Stainless steel column, 200 mm diameter, 300 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390062
Glass column, 200 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390063
Glass column, 200 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390064
Acrylic column, 200 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390106
Glass column, 300 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390107
Stainless steel column, 300 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390108
Stainless steel column, 300 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390113
Stainless steel column, 300 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390114
Acrylic column, 300 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390154
Stainless steel column, 350 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390155
Acrylic column, 350 mm diameter, 600 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390158
Stainless steel column, 350 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390159
Stainless steel column, 350 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390112
Glass column, 300 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
(Discontinued)Bio-Rad EasyPack Column

7390313
Stainless steel column, 600 mm diameter, 900 mm tube height, for process chromatography

This product is no longer available. Please contact technical support for more information on replacement product.
Number Description Options
5739 Packing and Slurry-in-Place Procedures for CHT Ceramic Hydroxyapatite Using a Bio-Rad InPlace Process-Scale Chromatography Column, Rev A Click to download [ Add to Cart (Free) ]
5657 Bio-Rad Process Chromatography Skid Product Information Sheet, Rev B Click to download [ Add to Cart (Free) ]
5488 State-of-the-Art Solutions for Process-Scale Chromatography, Rev C Click to download [ Add to Cart (Free) ]
5662 Process Chromatography Applications Laboratory Brochure, Rev B Click to download
5663 Bio-Rad InPlace Columns Product Information Sheet, Rev B Click to download [ Add to Cart (Free) ]
5661 Bio-Rad Media Transfer Device, Rev B Click to download [ Add to Cart (Free) ]
5739 Packing and Slurry-in-Place Procedures for CHT Ceramic Hydroxyapatite Using a Bio-Rad InPlace Process-Scale Chromatography Column, Rev A Click to download [ Add to Cart (Free) ]
5620 Bio-Rad Media Slurry Tank Product Information Sheet, Rev A Click to download
5659 Bio-Rad Mainframe Lifting Accessory Product Information Sheet, Rev B Click to download [ Add to Cart (Free) ]
5614 Bio-Rad Bubble Trap Product Information Sheet, Rev B Click to download
5615 Isolation Two-Way Valves Product Information Sheet, Rev A Click to download
5619 Pressure Relief Valve Product Information Sheet, Rev A Click to download
5616 Liquid Pump for Inflatable Seals Product Information Sheet, Rev B Click to download
5618 Pressure Gauge Product Information Sheet, Rev A Click to download

This product contains electrical or electronic material. Learn more about Bio-Rad's EU Recycle Program

Get Help
Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.