Bio-Plex Pro™ Human Cancer Biomarker Assays

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Bio-Plex Pro Human Cancer Biomarker Assays

Overview

Available Bio-Plex Pro™ Human Cancer Biomarker Assays
Panel 1
16-Plex
(171-AC500M)
Singleplex Sets
Bead Regions
sEGFR 171-BC501M 15
FGF-basic 171-BC502M 44
Follistatin 171-BC503M 26
G-CSF 171-BC504M 57
HGF
171-BC505M 62
sHER-2/neu 171-BC506M 12
sIL-6Rα 171-BC507M 19
Leptin 171-BC508M 78
Osteopontin 171-BC509M 77
PECAM-1 171-BC510M 46
PDGF-AB/BB 171-BC511M 47
Prolactin 171-BC512M 52
SCF 171-BC513M 65
sTIE-2 171-BC514M 64
sVEGFR-1 171-BC515M 76
sVEGFR-2 171-BC516M 45

Panel 2
18-Plex
(171-AC600M)
Singleplex Sets
Bead Regions
Angiopoietin-2 171-BC601M 47
sCD40L 171-BC602M 29
EGF 171-BC603M 14
Endoglin 171-BC604M 26
sFASL 171-BC605M 35
HB-EGF 171-BC606M 57
IGFBP-1 171-BC607M 62
IL-6 171-BC608M 19
IL-8 171-BC609M 54
IL-18* 171-BC610M 42
PAI-1 171-BC611M 61
PLGF 171-BC612M 52
TGF-α 171-BC613M 76
TNF-α 171-BC614M 36
uPA 171-BC615M 78
VEGF-A 171-BC616M 45
VEGF-C 171-BC617M 64
VEGF-D 171-BC618M 43

 

* IL-18 is not available as a singleplex set.

 

Bio-Plex Pro™ Human Cancer Biomarker Assay Specifications
 
Assay Sensitivity, pg/ml Assay Working Range, pg/ml
Panel 1 Targets LOD LLOQ ULOQ
sEGFR 3.5 11.9 195,000
FGF-basic 5.1 10.2 4,500
Follistatin 1.5 4.6 42,750
G-CSF 1.1 1.1 18,000
HGF
1.8 4.5 42,124
sHER-2/neu 0.5 1.4 23,500
sIL-6Rα 0.5 1.4 12,985
Leptin 1.1 7.3 119,429
Osteopontin 56.4 72.5 216,000
PECAM-1 24.4 51.5 135,000
PDGF-AB/BB 0.7 2.1 35,000
Prolactin 7.0 12.2 200,000
SCF 0.1 2.0 32,000
sTIE-2 6.6 12.2 200,000
sVEGFR-1 0.8 4.3 35,324
sVEGFR-2 7.4 12.1 197,681
Panel 2 Angiopoietin-2 3.3 19.5 51,100
sCD40L 0.3 1.4 18,405
EGF 0.1 0.3 4,942
Endoglin 1.0 3.3 54,740
sFASL 2.7 7.5 13,455
HB-EGF 0.1 0.3 4,314
IGFBP-1 1.5 4.2 39,514
IL-6 0.1 0.7 11,489
IL-8 0.1 0.4 4,943
IL-18* 0.3 1.6 25,798
PAI-1 0.2 3.7 59,826
PLGF 0.2 0.6 9,590
TGF-α 0.2 0.6 7,858
TNF-α 0.2 0.6 9,572
uPA 0.1 0.9 14,934
VEGF-A 0.4 1.7 27,518
VEGF-C 2.3 3.6 58,521
VEGF-D 11.5 14.0 17,614


*IL-18 is not available as a singleplex set.

 

Bio-Plex Assay Builder

To design your customized Express or x-Plex assay, process your catalog number, and obtain pricing information, launch the Assay Builder

To create a Bio-Plex custom assay, click Launch Bio-Plex Assay Builder.

Launch Bio-Plex Assay Builder



Using Bio-Plex® Technology for Disease Research

Bio-Plex Pro Human Cancer Biomarker Assays are a unique blend of magnetic bead–based assays designed to meet the needs of the most discerning preclinical and clinical researchers. The multiplex format enables robust and reproducible measurement of 34 cancer biomarkers involved in disease processes such as:

  • Angiogenesis
  • Metastasis
  • Cell proliferation
  • Cell adhesion/migration
  • Apoptosis
  • Inflammation

Bio-Plex Pro Human Cancer Biomarker Assays are available in two panels.

Panel 1 consists of receptors, cytokines, chemokines, growth factors, and hormones and is available as a premixed 16-plex all-in-one kit.

Panel 2 consists of ligands for panel 1, cytokines, chemokines, and growth factors and is available as a premixed 18-plex all-in-one kit.

Both panels are available in customizable analyte configurations and singleplex sets.

Panel 1

  • sEGFR
  • FGF-basic
  • Follistatin
  • G-CSF
  • sHER-2/neu
  • HGF
  • sIL-6Rα
  • Leptin
  • Osteopontin
  • PDGF-AB/BB
  • PECAM-1
  • Prolactin
  • SCF
  • sTIE-2
  • sVEGFR-1
  • sVEGFR-2

Panel 2

  • Angiopoietin-2
  • sCD40L
  • EGF
  • Endoglin
  • sFASL
  • HB-EGF
  • IGFBP-1
  • IL-6
  • IL-8
  • IL-18*
  • PAI-1
  • PLGF
  • TGF-α
  • TNF-α
  • uPA
  • VEGF-A
  • VEGF-C
  • VEGF-D

Based on 6.5 µm magnetic beads, these assay panels are compatible with both vacuum and magnetic wash stations. Magnetic washing simplifies plate processing, provides increased throughput, and results in decreased variability and increased reproducibility.

Key Features

  • Magnetic beads for simplified plate processing
  • All-in-one, space-saving complete kits
  • Premixed standards for generation of curves over a broad dynamic range for each target
  • Reagent kit II for reliable performance in serum and plasma samples
  • Optimized protocol for high precision and broad assay working ranges
  • Assay quick guide to get you started right away
  • 2-level quality controls included with premixed kits

Other Assay Formats Available

Instrument Compatibility

More Information

See how Bio-Plex instruments and assays benefit researchers studying heart disease, leukemia, melanoma, and other cancers.

Related Products

Bio-Plex Pro™ Human Inflammation Assays
For the first time, the key biomarkers of inflammation from the TNF superfamily proteins, IFN family proteins, Treg cytokines, and MMPs can be measured using a single multiplex kit. Bio-Plex Pro Human Inflammation Assays are available in larger 24-plex and 37-plex screening panels and a pathway-focused Treg 12-plex panel, along with singleplex and custom-configured assays.

Bio-Plex Pro™ Human Cancer Biomarker Panel 1, 16-plex

171-AC500M
1 x 96-well, includes coupled magnetic beads, detection antibodies, standards, controls, buffers, diluents, streptavidin-PE, flat bottom plate, sealing tape, for the detection of 16 human cancer biomarkers

List Price:   $2,649.00
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io-Plex Pro Human Cancer Biomarker Panel 2, 18-plex (#171-AC600M) - Bio-Plex Pro Human Cancer Assays
Bio-Plex Pro™ Human Cancer Biomarker Panel 2, 18-plex

171-AC600M
1 x 96-well, includes coupled magnetic beads, detection antibodies, standards, controls, buffers, diluents, streptavidin-PE, flat bottom plate, sealing tape, for the detection of 18 human cancer biomarkers

List Price:   $2,885.00
Your Price:   Log in
Quantity:   Add to cart
Add to Hot List   Add to Quote
Number Description Options
6532 Cross-Reactivity of Bio-Plex Pro Human Cancer Biomarker Assays to Mouse Proteins, Rev A Click to download
6159 Bio-Plex Pro Human Cancer Biomarker Panels, Rev B Click to download [ Add to Cart (Free) ]
6335 Bio-Plex® Multiplex Immunoassays Analyte Guide, Interactive PDF, Rev D Click to download [ Add to Cart (Free) ]
6304 Development and Validation of Bio-Plex Pro Human Cancer Biomarker Panel 2, Rev A Click to download [ Add to Cart (Free) ]
6156 Composite Profiling of Angiogenic Factors Using Bio-Plex Pro Human Cancer Biomarker Panel 1, Rev A Click to download [ Add to Cart (Free) ]
5405 Bio-Plex Multiplex System Brochure, Rev D Click to download [ Add to Cart (Free) ]
10022581 Instruction Manual, Bio-Plex Pro Assays Quick Guide, Rev C Click to download
10022186 Instruction Manual, Bio-Plex Pro Human Cancer Biomarker Assays, Rev B Click to download
6330 Profiling of Cell Signaling Pathways and Angiogenesis Biomarkers in Human Cancer Tissue Click to download
6457 The Bio-Plex Success Guide for Multiplex Immunoassays, Rev B Click to download
6458 Bio-Plex Success Guide/Assay Sample Prep, Rev B Click to download