Bio-Beads™ SM-2 Resin



Product Selection by Technique
Chromatography Product Selection by Technique*
Packaging Format
Characteristics Product Type Analytical Pilot/Preparative Process Prepacked Bottled
Ion Exchange Chromatography
Separation by charge UNOsphere media     UNOsphere Q, S, rapid S
General biomolecules purification Macro-Prep media     Macro-Prep High Q, DEAE, High S, CM
Applicable to all antibody purifications Macro-Prep 25 media     Macro-Prep 25 Q, 25 S
UNO columns   UNO Q, S  
Bio-Scale Mini Cartridges     UNOsphere Q, S  
High capacity         Macro-Prep High Q, S  
Good Capture technique AG resins   AG
Chelex resins Chelex
Bio-Rex resins Bio-Rex
Hydroxyapatite and Fluoroapatite Chromatography
Unique Selectivity CHT 80 µm support     CHT, Types I and II
Alternative to protein A for antibody purification CHT 40 µm support     CHT, Types I and II
CHT 20 µm support   CHT, Types I and II
CFT 40 µm support CFT, Types I and II
Removal of leached protein A, aggregates, endotoxins, and DNA Bio-Gel HT and HTP media     Bio-Gel HT, HTP
Bio-Scale columns   CHT Type I (10 µm)  
CHT Type II (20 µm)  
Affinity Chromatography
Purification of His- and GST- tagged proteins Profinity IMAC and GST media   Bio-Scale Mini Profinity IMAC
Separation by biological interaction Affi-Gel resins     Affi-Gel Protein A**
Affi-Gel Blue**
DEAE Affi-Gel Blue**
CM Affi-Gel Blue**
High selectivity           Affi-Gel boronate, heparin**
High purity in a single step           Affi-Gel Hz, 10, 15***
Affi-Gel 102***
Excellent capture technique Profinity epoxide media     Profinity epoxide***
Affi-Prep media   Affi-Prep protein A**
Affi-Prep polymyxin**
Bio-Scale Mini cartridges   Profinity IMAC and GST  
Econo-Pac columns   Affi-Gel Blue  
DEAE Affi-Gel Blue
Affi-Gel protein A
Size Exclusion Chromatography
Separation by size Bio-Gel P media     Bio-Gel P
MW determination Bio-Beeds S-X media     Bio-Beads S-X
Applicable to all antibody purifications Bio-Sil and Bio-Silect columns     Bio-Sil, Bio-Silect  
Desalting or buffer exchange Bio-Scale Mini cartridges     Bio-Gel P-6  
High resolution Econo-Pac columns     Econo-Pac 10DG  
Hydrophobic Interaction Chromatography
Separation by hydrophobicity Macro-Prep HIC media     Macro-Prep t-butly
Macro-Prep methyl

** Ready to use.
*** Activated.

Compounds Concentrated or Separated by Bio-Beads SM Adsorbents
Trace organics Morphine
PAH compounds Methaqualone
Hydrocarbons and PCBs Sulfas
Aminocrab insecticides Free rhodamine
Carbamate insecticides Prostaglandins
Ethyl and methyl parathion Steriods
Metals Bile acids
Carboxylic acids Hormones
Phenolic acids Purines and pyrimidines
Flavonoids Acid dyes
Mycotoxins Naringin and limonin
Proline and hydroxyproline Detergents

Bio-Beads SM-2 adsorbents are analytical-grade, neutral macroporous polymeric beads with a high surface area for adsorbing organics with MW <2,000 from aqueous solutions. These beads can be used in aqueous solution with solvents including alcohols, petroleum ether, diethyl ether, and hexane, or with solvent mixtures, without expansion or contraction of the beads.

Bio-Beads SM-2 nonpolar polystyrene adsorbents are useful for the adsorption of nonpolar substances or surface active agents from aqueous solutions.

Common applications of Bio-Beads SM-2 adsorbents include:

  • Removal of detergents such as Triton X-100
  • Removal of organics such as polyaromatic hydrocarbons from water
  • Cleanup of drugs from plasma and urine
  • Cleanup of biological metabolites and pesticides
  • Extraction of dyes and mycotoxins from food products


Composition Polystyrene divinylbenzene
Polarity Nonpolar
Dipole moment 0
Bead size 300–1,180 µm
Average pore diameter 90 Å (dry beads)
Surface area 300 m2/g
Wet density 1.02 g/ml
Bio-Beads SM-2 Adsorbents

100 g, nonpolar polystyrene adsorbents for hydrophobic interaction chromatography, 300–1,180 µm bead size, for organics MW <2,000

List Price:   $450.00
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Bio-Beads SM-2 Adsorbents

25 g, biotechnology grade nonpolar polystyrene adsorbents for hydrophobic interaction chromatography, 300–1,180 µm bead size, for organics MW <2,000

List Price:   $120.00
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Number Description Options
1461 Bio-Beads SM-2 Hydrophobic Adsorbents Application Bibliography Click to download
LIT195 Instruction Manual, Bio-Beads SM Hydrophobic and Polar Interaction Adsorbents, Rev B Click to download