Alphafetoprotein Antigen (AFP)

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Alphafetoprotein Antigen (AFP)


AFP is a 70 kD major fetal serum glycoprotein with an unknown function that is synthesized in the liver, yolk sac and fetal gastrointestinal tract. Serum elevations are seen in either pregnant women or patients with cirrhosis and hepatitis. Increases in serum levels aid in diagnosis, classification and monitoring of non-seminomatous testicular cancer as well as primary hepatocellular carcinoma. This antigen is derived from a liver tumor cell and not human cord serum. It contains the correct isoform percentage of AFP-L3 (approximately 70% as compared to 10% in human cord serum).

AFP has three isoforms (AFP-L1, AFP-L2 and AFP-L3) of which the AFP-L3 form is associated with germ cell and liver tumors.

Approved clinical uses includes diagnosis, classification and monitoring of non-seminomatous testicular and heptacellular carcinomas.

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AFP Ag., CC, HP

13752600
Source: Human Hepatocarcinoma Cell Line. Concentration: 2-5 mg/mL. Form: 0.1M Tris, 0.2M NaCl, 0.1% NaN3, pH 7.5 ± 0.2

13752600 /templatedata/internet/product_SKU/data/CDG/Critical-Raw-Materials/Antigens/13752600_1358449218.xml 13752600 01/17/13 10:58 AM en_US true internet/product_SKU 2019-03-07 01:50:27 /default/main/bio-rad/STAGING AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA templatedata/internet/product_SKU/data/CDG/Critical-Raw-Materials/Antigens/13752600_1358449218.xml /default/main/bio-rad/WORKAREA/default jcc1togd 2017-11-14 07:06:24 true jcc1togd templatedata/internet/product_SKU/data/CDG/Critical-Raw-Materials/Antigens/13752600_1358449218.xml CDG N /default/main/bio-rad en 02/14/23 11:58 AM 1544839605459 2019-03-07 01:50:27 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Critical-Raw-Materials/Antigens/13752600_1358449218.xml 13752600-afp-ag-cc-hp 1 13752600 AFP Ag., CC, HP AFP Ag., CC, HP Source: Human Hepatocarcinoma Cell Line. Concentration: 2-5 mg/mL. Form: 0.1M Tris, 0.2M NaCl, 0.1% NaN<sub>3</sub>, pH 7.5 &plusmn; 0.2 Source: Human Hepatocarcinoma Cell Line. Concentration: 2-5 mg/mL. Form: 0.1M Tris, 0.2M NaCl, 0.1% NaN<sub>3</sub>, pH 7.5 &plusmn; 0.2 /webroot/web/images/cdg/products/critical_raw_materials/sku_thumb/global/crm_13752600_tn.jpg /webroot/web/images/cdg/products/critical_raw_materials/sku_view/global/crm_13752600_view.jpg /webroot/web/images/cdg/products/critical_raw_materials/sku_feature/global/crm_13752600_feature.jpg AFP Ag., CC, HP Leor AFP Ag., CC, HP Source: Human Hepatocarcinoma Cell Line. Concentration: 2-5 mg/mL. Form: 0.1M Tris, 0.2M NaCl, 0.1% NaN<sub>3</sub>, pH 7.5 &plusmn; 0.2 AFP Ag., CC, HPSource: Human Hepatocarcinoma Cell Line. Concentration: 2-5 mg/mL. Form: 0.1M Tris, 0.2M NaCl, 0.1% NaN<sub>3</sub>, pH 7.5 &plusmn; 0.2 01/17/13 10:58 AM 02/14/23 11:58 AM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Critical-Raw-Materials/Antigens N 0 <p><strong>Grade:</strong> Highly Purified<br /><strong>Concentration:</strong> 2-5 mg/mL<br /><strong>Source:</strong> Human Hepatocarcinoma Cell Line<br /><strong>Form:</strong> Liquid in 0.1M Tris, 0.2M NaCl, 0.1% NaN<sub>3</sub>, pH 7.5 &plusmn; 0.2<br /><strong>Filtration:</strong> 0.2&micro;<br /><strong>Use:</strong> This highly purified product is normally used as an immunogen or for labeling, but is also suitable for multi-analyte controls.<br /><strong>Specificty:</strong> Western blot<br /><strong>Purity:</strong> &gt;95% by PAGE Analysis<br /><strong>Total Protein:</strong> 0.5&ndash;5 O.D. units<br /><strong>Storage:</strong> -20&deg;C<br /><strong>Shelf Life:</strong>&nbsp;3 years at -20&deg;C<br /><strong>Viral testing:</strong> The cell line supernatants tested negative for HIV-1, HIV-2, HIV-1 Ag, HBsAg, HCV Ab and HCV Ag (NAT by FDA accepted methods).</p> /webroot/web/html/cdg/products/critical_raw_materials/sku_view/description/global crm_afp_ag_cc_hp_sku_desc.html /webroot/web/html/cdg/products/critical_raw_materials/sku_view/description/global/crm_afp_ag_cc_hp_sku_desc.html 1 0 false null false $ null false false true true false USD true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=13752600&quantity= false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=13752600&CartQuote=QT&quantity= 2980 false true false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=13752600&AddToDefaultWishList=true&quantity= 12352200 null 13752600
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